Results 71 to 80 of about 4,919,522 (294)

[Atorvastatin in secondary prevention].

Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2009
During the 10 years of atorvastatin availability in the Turkish market, the physicians have had the opportunity to observe the accumulation of data related to its beneficial effect on clinical endpoints. The scope of this review is limited to the trials concerning the role of atorvastatin in secondary prevention.
Ongen, Zeki, Yilmaz, Yesim, Karadag, Bilgehan   +2 more
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Práticas de autocuidado em hanseníase: face, mãos e pés

Revista Gaúcha de Enfermagem, 2018
Resumo OBJETIVO Analisar as práticas de autocuidado em face, mãos e pés realizadas por pessoas atingidas pela hanseníase. METODOLOGIA Estudo qualitativo, realizado em unidades de referência para hanseníase em Pernambuco, entre maio de 2014 e abril de ...
Marize Conceição Ventin Lima, Fernanda Ribeiro Barbosa, Danielle Christine Moura dos Santos, Raphaela Delmondes do Nascimento, Stephanie Steremberg Pires D’Azevedo   +4 more
doaj   +1 more source

Secondary Prevention

Abstract Secondary prevention tackles the difficult challenge of addressing the sequelae of IPV, during its “early stages,” both providing interventions so that IPV doesn’t happen again and before more acute or critical tertiary services are needed.
Carmine Morisco, Alessandro Bellis, Ciro Mauro, Bruno Trimarco   +3 more
  +5 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Secondary Stroke Prevention in People With Schizophrenia

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background People with schizophrenia are less likely than those without to be treated for cardiovascular disease. We aimed to evaluate the association between schizophrenia and secondary preventive care after ischemic stroke.
Moira K. Kapral, Joan Porter, Paul Kurdyak, Amy Y. X. Yu, Emilie Matheson, Jiming Fang, Leanne K. Casaubon, Eshita Kapoor, Kathleen A. Sheehan   +8 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Workaholism – Indications for diagnosis and review of interventions

Medycyna Pracy, 2015
Due to numerous psychological and health costs, the issue of workaholism requires taking appropriate actions by relevant specialists, including occupational medicine services.
Diana Malinowska, Sabina Staszczyk, Aleksandra Tokarz   +2 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

ACETYLSALICYLIC ACID IN PRIMARY AND SECONDARY PREVENTION OF STROKE

Атеротромбоз, 2017
Prevention of stroke remains one of the most pressing healthcare issues. Acetylsalicylic acid (ASA) is the only antithrombotic drug used for primary and secondary prevention of atherothrombotic stroke.
P. S. Laguta
doaj   +1 more source