Results 81 to 90 of about 18,469,580 (392)

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

In silico identification of papaya genome-encoded microRNAs to target begomovirus genes in papaya leaf curl disease

Frontiers in Microbiology
Papaya leaf curl disease (PaLCuD) is widespread and classified in the genus begomovirus (Geminiviridae), disseminated by the vector whitefly Bemisia tabaci. RNA interference (RNAi)-based antiviral innate immunity stands as a pivotal defense mechanism and
Aarshi Srivastava, Vineeta Pandey, Nupur Singh, Avinash Marwal, Muhammad Shafiq Shahid, R. K. Gaur   +5 more
doaj   +1 more source

Probing the Structures of Viral RNA Regulatory Elements with SHAPE and Related Methodologies

Frontiers in Microbiology, 2018
Viral RNAs were selected by evolution to possess maximum functionality in a minimal sequence. Depending on the classification of the virus and the type of RNA in question, viral RNAs must alternately be replicated, spliced, transcribed, transported from ...
Jason W. Rausch, Joanna Sztuba-Solinska, Joanna Sztuba-Solinska, Stuart F. J. Le Grice   +3 more
doaj   +1 more source

A Novel Motif in the 3′-UTR of PRRSV-2 Is Critical for Viral Multiplication and Contributes to Enhanced Replication Ability of Highly Pathogenic or L1 PRRSV

Viruses, 2022
Highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) with enhanced replication capability emerged in China and has become dominant epidemic strain since 2006.
Junyao Xiong, Xingyang Cui, Kuan Zhao, Qian Wang, Xinyi Huang, Dongyan Li, Fang Yu, Yongbo Yang, Di Liu, Zhijun Tian, Xuehui Cai, Tongqing An   +11 more
doaj   +1 more source

Internal ribosomal entry site lacks secondary structure [PDF]

, 2007
The search for mechanisms of translational regulation has yielded many experimentally identified internal ribosome entry sites (IRES). Because of the lack of sequence similarity among the experimentally IRESs, it is widely assumed that IRESs posses ...
Xuhua Xia
core   +1 more source

Jeeva: Enterprise Grid-enabled Web Portal for Protein Secondary Structure Prediction [PDF]

, 2008
This paper presents a Grid portal for protein secondary structure prediction developed by using services of Aneka, a .NET-based enterprise Grid technology.
Buyya, Rajkumar, Gubbi, Jayavardhana, Jin, Chao, Palaniswami, Marimuthu   +3 more
core   +3 more sources

The hydration of protein secondary structures

FEBS Letters, 1987
The hydration of the main‐chain carbonyl (CO) groups in proteins have been studied using infra‐red spectroscopy, and computer‐graphics analysis of high resolution protein crystal structures. The IR measurements indicate that the strength of water binding to the CO groups is lower in β‐sheet proteins compared with α‐helical ones. Analysis of the protein
P.L. Poole, David J. Barlow
openaire   +3 more sources

Sixty-five years of the long march in protein secondary structure prediction: the final stretch?

Briefings Bioinform., 2016
Protein secondary structure prediction began in 1951 when Pauling and Corey predicted helical and sheet conformations for protein polypeptide backbone even before the first protein structure was determined.
Yuedong Yang, Jianzhao Gao, Jihua Wang, Rhys Heffernan, Jack Hanson, K. Paliwal, Yaoqi Zhou   +6 more
semanticscholar   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Thermal gel properties and protein conformation of pork batters as affected by high pressure and temperature

International Journal of Food Properties, 2019
Effects of different temperatures (20–60°C) on gel characteristics, rheology, and protein conformations of pork batters produced by high pressure prior to heating were studied.
Li-Peng Wei, Yan-Ping Li, Chun-Yan Wang, Zhuang-Li Kang, Han-Jun Ma   +4 more
doaj   +1 more source