Results 201 to 210 of about 7,510,806 (303)

Quantification of Protein Secondary Structures from Discrete Frequency Infrared Images Using Machine Learning. [PDF]

Appl Spectrosc
Edmonds H, Mukherjee SS, Holcombe B, Yeh K, Bhargava R, Ghosh A.   +5 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

How DNA secondary structures drive replication fork instability.

DNA Repair (Amst)
Sethi A, Fernández-Casañas M, Delpino B, Coster G.   +3 more
europepmc   +1 more source

Comparative analysis of predicted DNA secondary structures infers complex human centromere topology. [PDF]

Am J Hum Genet
Chittoor SS, Giunta S.
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Secondary Structures of Human Calcitonin at Different Temperatures and in Different Membrane-Mimicking Environments, Characterized by Circular Dichroism (CD) Spectroscopy. [PDF]

ACS Omega
Wärmländer SKTS, Lakela AL, Berntsson E, Jarvet J, Gräslund A.   +4 more
europepmc   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Backbone interactions and secondary structures in phase separation of disordered proteins. [PDF]

Biochem Soc Trans
Li S, Zhang Y, Chen J.
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Chikungunya Virus RNA Secondary Structures Impact Defective Viral Genome Production. [PDF]

Microorganisms
Levi LI, Madden EA, Boussier J, Erazo D, Sanders W, Vallet T, Bernhauerova V, Moorman NJ, Heise MT, Vignuzzi M.   +9 more
europepmc   +1 more source