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Modeling secondary structures and secondary structure linkages of protein sequences
2010 IEEE International Conference on Systems, Man and Cybernetics, 2010In this paper we model protein secondary structures such as a-helices and b sheets and linkages thereof using passive electrical circuit components and obtain the frequency responses of these circuits. An analysis of the frequency responses of these model circuits shows that putative connections can be made between circuit behavior and known ...
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Secondary Structure and Protein Deamidation
Journal of Pharmaceutical Sciences, 1999The deamidation reactions of asparagine residues in alpha-helical and beta-turn secondary structural environments of peptides and proteins are reviewed. Both kinds of secondary structure tend to stabilize asparagine residues against deamidation, although the effects are not large.
M, Xie, R L, Schowen
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Journal of Theoretical Biology, 1977
Abstract The complete set of possible secondary structures of a variant Qβ RNA sequenced by Schaffner has been found using a computer program which allows G-U pairing as well as the usual Watson-Crick A-U and G-C pairing. Of special interest are those secondary structures with the highest double-strandedness.
I R, Lapidus, B, Rosen, R, Hepperle
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Abstract The complete set of possible secondary structures of a variant Qβ RNA sequenced by Schaffner has been found using a computer program which allows G-U pairing as well as the usual Watson-Crick A-U and G-C pairing. Of special interest are those secondary structures with the highest double-strandedness.
I R, Lapidus, B, Rosen, R, Hepperle
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Similarity of RNA secondary structures
Journal of Computational Chemistry, 2006AbstractIn this article, we propose a relatively similar measure to compare RNA secondary structures. We first transform an RNA secondary structure into a special sequence representation. Then, on the basis of symbolic sequence complexity, we obtain the relative distance of RNA secondary structures.
Chun Li, Ai-hua Wang, Lili Xing
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The protein secondary structure flexibility
2008Modeling protein flexibility is a long standing challenge in computational biology with a special impact to protein docking. Relating problems are protein structures alignment and identification of flexible and rigid protein regions, as well as a general definition of a region degree of flexibility.
Šikić, Krešimir +2 more
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Characterization of protein secondary structure
IEEE Signal Processing Magazine, 2004What do proteins look like? Proteins are composed of fundamental building blocks of chemical molecules called amino acids. When a protein is synthesized by the cells, initially it is just a string of amino acids. This string arranges itself in a process called protein folding into a complex three-dimensional structure capable of exerting the function ...
Madhavi K. Ganapathiraju +3 more
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2010
In principle we could expect that X-ray diffraction provides a complete picture of any protein that can be crystallized, with the exact position of each atom. Indeed, models displayed in showcases give the impression that the protein structure is fully known and has been found ab initio.
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In principle we could expect that X-ray diffraction provides a complete picture of any protein that can be crystallized, with the exact position of each atom. Indeed, models displayed in showcases give the impression that the protein structure is fully known and has been found ab initio.
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RNA Secondary Structure an Overview
2018It was believed that the single role of the Ribonucleic acid (RNA) is to carry the information necessitate to build a specific protein. Now it discovered that RNA has important and essential roles in many gene regulatory networks and many other cellular functions.
Abdelhakim El Fatmi +4 more
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Targeting DNA Secondary Structures
Current Medicinal Chemistry, 2000DNA secondary structures containing regions of single-stranded DNA have now been identified in the genomic DNA of a number of prokaryotic and eukaryotic species, including humans. Many of these secondary structures are associated with regions of DNA involved in regulation of transcription: promoters or upstream elements.
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Secondary Structure of Ribosomal RNA
Science, 1970Infrared spectra were obtained for 16 S and for 23 S ribosomal RNA's in D 2 O solutions. The percentage of each base in the paired and unpaired regions of the RNA was determined from the spectra. The secondary structures of 16 S and 23
K A, Hartman, G J, Thomas
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