Results 131 to 140 of about 11,220 (181)
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Scandinavian Journal of Gastroenterology, 1978
Because secretin tests have been used to establish the Zollinger-Ellison (Z-E) diagnosis, the effects of i.v. infusion (1 CU/kg/h) or injection (1 CU/kg) of secretin on serum concentrations of gastrin in hypersecretors with a verified Z-E diagnosis (n = 25) or duodenal ulcer disease (n = 19) were compared.
F Stadil +1 more
exaly +3 more sources
Because secretin tests have been used to establish the Zollinger-Ellison (Z-E) diagnosis, the effects of i.v. infusion (1 CU/kg/h) or injection (1 CU/kg) of secretin on serum concentrations of gastrin in hypersecretors with a verified Z-E diagnosis (n = 25) or duodenal ulcer disease (n = 19) were compared.
F Stadil +1 more
exaly +3 more sources
Gastroenterology, 1978
Several sensitive radioimmunoassay systems for secretin have been developed and reported1–6. The development of these assay systems depended upon the generation of a specific secretin antiserum and the iodination of secretin (natural porcine secretin, synthetic secretin or a tyrosyl derivative of secretin).
P L, Rayford +2 more
openaire +4 more sources
Several sensitive radioimmunoassay systems for secretin have been developed and reported1–6. The development of these assay systems depended upon the generation of a specific secretin antiserum and the iodination of secretin (natural porcine secretin, synthetic secretin or a tyrosyl derivative of secretin).
P L, Rayford +2 more
openaire +4 more sources
On the instability of secretin
Life Sciences, 1981Abstract Secretin has repeatedly been said to be unstable. We found that the biological potency of secretin solutions under some conditions decreased. We tested hypotheses about the cause(s). Adsorption of secretin on materials in which it is stored may account for most of the rapid decrease of biological potency.
H C, Beyerman +4 more
openaire +2 more sources
2003
Secretin, a 27-amino-acid peptide hormone produced by intestinal S cells, is released into the duodenum primarily in response to pH changes following food ingestion. Its major target organs include the pancreas, stomach, and gallbladder. Secretin affects pancreatic bicarbonate secretion, gastric acid secretion, and motility and augmentation of bile ...
De La Fuente, S. G., Pappas, T. N.
openaire +2 more sources
Secretin, a 27-amino-acid peptide hormone produced by intestinal S cells, is released into the duodenum primarily in response to pH changes following food ingestion. Its major target organs include the pancreas, stomach, and gallbladder. Secretin affects pancreatic bicarbonate secretion, gastric acid secretion, and motility and augmentation of bile ...
De La Fuente, S. G., Pappas, T. N.
openaire +2 more sources
Different actions of secretin and Gly-extended secretin predict secretin receptor subtypes
American Journal of Physiology-Gastrointestinal and Liver Physiology, 2001Only one secretin receptor has been cloned and its properties characterized in native and transfected cells. To test the hypothesis that stimulatory and inhibitory effects of secretin are mediated by different secretin receptor subtypes, pancreatic and gastric secretory responses to secretin and secretin-Gly were determined in rats.
T E, Solomon +5 more
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Secretin: A Pleiotrophic Hormone
Annals of the New York Academy of Sciences, 2006Abstract: Secretin holds a unique place in the history of endocrinology and gastrointestinal physiology, as it is the first peptide designated as a hormone. During the last century since its first discovery, the hormonal effects of secretin in the gastrointestinal tract were extensively studied, and its principal role in the periphery was found to ...
Chow, BKC, Chu, JYS, Yung, WH
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Comprehensive Physiology, 1989
Abstract The sections in this article are: Discovery of Secretin Historical Background Isolation and Purification of Secretin ...
William Y. Chey, Ta‐Min Chang
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Abstract The sections in this article are: Discovery of Secretin Historical Background Isolation and Purification of Secretin ...
William Y. Chey, Ta‐Min Chang
openaire +1 more source
1958
Publisher Summary The mucosal lining of the alimentary tube forms a number of hormones which regulate the motor and secretory activities of the organs of digestion. The existence of five such hormones can be considered to be well established, which are: (1) gastrin, which stimulates gastric acid secretion, (2) cholecystokinin, which causes ...
openaire +2 more sources
Publisher Summary The mucosal lining of the alimentary tube forms a number of hormones which regulate the motor and secretory activities of the organs of digestion. The existence of five such hormones can be considered to be well established, which are: (1) gastrin, which stimulates gastric acid secretion, (2) cholecystokinin, which causes ...
openaire +2 more sources
2013
Since its initial discovery, secretin is now coined as a classical hormone with widespread distribution. In particular, numerous studies have demonstrated the abundant expression of secretin and its receptor within various brain areas sparking interest of its potential as a brain peptide.
Cheng, CYY, Ng, SYL, Chow, BKC
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Since its initial discovery, secretin is now coined as a classical hormone with widespread distribution. In particular, numerous studies have demonstrated the abundant expression of secretin and its receptor within various brain areas sparking interest of its potential as a brain peptide.
Cheng, CYY, Ng, SYL, Chow, BKC
openaire +4 more sources
Journal of Child and Adolescent Psychopharmacology, 1998
R, Perry, B S, Bangaru
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R, Perry, B S, Bangaru
openaire +2 more sources