Neuroendocrine chromaffin cells represent an excellent model to study the molecular mechanisms associated with the exo-endocytotic cycle of neurotransmitter release.
Yolanda Gimenez-Molina +4 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Pathogen-induced protein secretion in plants.
The sugar alcohol mannitol is an important carbohydrate in many plants and fungi that has well-documented roles in both metabolism and osmoprotection. In addition, mannitol is an antioxidant, and as such might play a role in host-pathogen interactions ...
Cheng, Fang-yi
core
Regulation of fat-stimulated neurotensin secretion in healthy subjects [PDF]
CONTEXT: Cholecystokinin (CCK) and neurotensin are stimulated during meal intake by the presence of fat in the small intestine. The sequence of events suggests that fat hydrolysis is crucial for triggering the release.
Drewe, J. +3 more
core +1 more source
Nasal mucosa secretion exudation response to cold air in bronchial asthma patients
Background. Combined airway hyper responsiveness to cold and hypoosmotic stimuli in asthma patients results in impairment of lung respiration function and poor disease control compared to patients with isolated airway hyper responsiveness to only one of ...
Eduard V. Nekrasov +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Transzcelluláris bikarbonát szekréció és intracelluláris pH reguláció polarizált epitheliás sejtekben = Transcellular bicarbonate secretion and intracellular pH regulation on polarized epithelial cells [PDF]
Kutatásunk célja polarizált epitheliális sejtek elektrolit és folyadékszekréciójának molekuláris szintű vizsgálata volt. Jól differenciált hasnyálmirigy duktusz Capan-1 és HPAF, valamint nyálmirigy acinus ParC10 és SMIE sejtvonalakat vizsgáltunk ...
Burghardt, Beáta
core +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Epithelial organization and cyst lumen expansion require efficient Sec13-Sec31-driven secretion [PDF]
Epithelial morphogenesis is directed by interactions with the underlying extracellular matrix. Secretion of collagen and other matrix components requires efficient coat complex II (COPII) vesicle formation at the endoplasmic reticulum. Here, we show that
Schmidt, Katy +3 more
core +1 more source
Milk lipid secretion: recent biomolecular aspects
Neonates of most species depend on milk lipids for calories, fat-soluble vitamins, and bioactive lipid components for growth and development during the postnatal period.
McManaman James L.
doaj +1 more source

