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Cystic fibrosis (CF) is the most common genetic disorder that causes a significant damage in secretory epithelial cells due to the defective ion flux across the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel.
Tamara Madácsy+5 more
doaj +1 more source
Synaptotagmin-1 is the Ca2+ sensor for fast striatal dopamine release
Dopamine powerfully controls neural circuits through neuromodulation. In the vertebrate striatum, dopamine adjusts cellular functions to regulate behaviors across broad time scales, but how the dopamine secretory system is built to support fast and slow ...
Aditi Banerjee+4 more
doaj +1 more source
What are the Practices for Secret Management in Software Artifacts? [PDF]
Throughout 2021, GitGuardian's monitoring of public GitHub repositories revealed a two-fold increase in the number of secrets (database credentials, API keys, and other credentials) exposed compared to 2020, accumulating more than six million secrets. A systematic derivation of practices for managing secrets can help practitioners in secure development.
arxiv
Matroids and Quantum Secret Sharing Schemes [PDF]
A secret sharing scheme is a cryptographic protocol to distribute a secret state in an encoded form among a group of players such that only authorized subsets of the players can reconstruct the secret. Classically, efficient secret sharing schemes have been shown to be induced by matroids.
arxiv +1 more source
Genomic Analysis of ATP Efflux in Saccharomyces cerevisiae
Adenosine triphosphate (ATP) plays an important role as a primary molecule for the transfer of chemical energy to drive biological processes. ATP also functions as an extracellular signaling molecule in a diverse array of eukaryotic taxa in a conserved ...
Theodore W. Peters+5 more
doaj +1 more source
Influence of microclimatic conditions on nectar exudation in Glechoma hirsuta W. K [PDF]
The nectar production of Glechoma hirsuta W. K. grown under different microclimatic habitat conditions was evaluated by determining the total daily nectar quantity per flower, diurnal dynamics of nectar secretion, the nectar secretion rate, and sugar ...
Mačukanović-Jocić Marina+1 more
doaj +1 more source
Pituitary adenylate cyclase activating polypeptide (PACAP) is a multifunctional neuropeptide with widespread occurrence throughout the body including the gastrointestinal system.
Dora Reglodi+6 more
doaj +1 more source
Aims: To investigate whether idiopathic osteonecrosis of the femoral head (ONFH) is related to impaired osteoblast activities. Methods: We cultured osteoblasts isolated from trabecular bone explants taken from the femoral head and the intertrochanteric ...
Leila Maestro-Paramio+3 more
doaj +1 more source
Message Randomization and Strong Security in Quantum Stabilizer-Based Secret Sharing for Classical Secrets [PDF]
We improve the flexibility in designing access structures of quantum stabilizer-based secret sharing schemes for classical secrets, by introducing message randomization in their encoding procedures. We generalize the Gilbert-Varshamov bound for deterministic encoding to randomized encoding of classical secrets.
arxiv +1 more source
The secreted secret of PCSK9 [PDF]
Amgen researchers have demonstrated that blocking secreted PCSK9 in mice and nonhuman primates lowers LDL cholesterol. The findings bolster the case for an antibody-based approach to blocking the protein, which is a genetically validated target for hypercholesterolemia.
openaire +2 more sources