An investigation into the relationship between small intestinal fluid secretion and systemic arterial blood pressure in the anesthetized rat [PDF]
, 2015 In the absence of an ability to absorb fluid by cellular uptake mechanisms, fluid movement in vivo from the perfused rat intestine is absorptive when the diastolic blood pressure is normal or very low but is secretory when blood pressure falls below ...
Lucas, Michael, Morrison, James
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Hepatic inactivation of murine Surf4 results in marked reduction in plasma cholesterol
eLife, 2022 PCSK9 negatively regulates low-density lipoprotein receptor (LDLR) abundance on the cell surface, leading to decreased hepatic clearance of LDL particles and increased levels of plasma cholesterol.
Vi T Tang +10 more
doaj +1 more source
Insulin-like growth factor-1 is a negative modulator of glucagon secretion [PDF]
, 2017 Glucagon secretion involves a combination of paracrine, autocrine, hormonal, and autonomic neural mechanisms. Type 2 diabetes often presents impaired glucagon suppression by insulin and glucose.
Andreozzi, F +6 more
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Frontiers in Bioengineering and Biotechnology, 2020 Engineered microbes for the delivery of intestinally directed therapeutics is a promising avenue for the treatment of various intestinal diseases including inflammatory bowel disease (IBD) and intestinal graft vs. host disease (GVHD).
Laura Ortiz-Velez +5 more
doaj +1 more source
Influence of microclimatic conditions on nectar exudation in Glechoma hirsuta W. K [PDF]
Archives of Biological Sciences, 2005 The nectar production of Glechoma hirsuta W. K. grown under different microclimatic habitat conditions was evaluated by determining the total daily nectar quantity per flower, diurnal dynamics of nectar secretion, the nectar secretion rate, and sugar ...
Mačukanović-Jocić Marina +1 more
doaj +1 more source
Ferritin heavy chain Is the host factor responsible for HCV-Induced inhibition of apoB-100 production and is required for efficient viral infection [PDF]
, 2012 Hepatic fat export occurs by apolipoprotein B-100-containing lipoprotein production, whereas impaired production leads to liver steatosis. Hepatitis C virus (HCV) infection is associated to dysregulation of apoB-100 secretion and steatosis; however, the ...
AMICONE, Laura +9 more
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Bone & Joint Research, 2021 Aims: To investigate whether idiopathic osteonecrosis of the femoral head (ONFH) is related to impaired osteoblast activities. Methods: We cultured osteoblasts isolated from trabecular bone explants taken from the femoral head and the intertrochanteric ...
Leila Maestro-Paramio +3 more
doaj +1 more source
High-salinity growth conditions promote tat-independent secretion of tat substrates in Bacillus subtilis [PDF]
, 2012 The Gram-positive bacterium Bacillus subtilis contains two Tat translocases, which can facilitate transport of folded proteins across the plasma membrane. Previous research has shown that Tat-dependent protein secretion in B.
Alami +59 more
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Clinical Insights Into Hypercalcemia of Malignancy in Childhood
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source
The role of TcdB and TccC subunits in secretion of the photorhabdus Tcd toxin complex [PDF]
, 2013 The Toxin Complex (TC) is a large multi-subunit toxin encoded by a range of bacterial pathogens. The best-characterized examples are from the insect pathogens Photorhabdus, Xenorhabdus and Yersinia.
A Sisto +37 more
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