Results 101 to 110 of about 546,603 (232)

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

Molecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi, Sang‐Hyeon Yoo, Ki‐Jong Rhee   +2 more
wiley   +1 more source

Adsorption and elution study detected misidentification of para-Bombay phenotype donor in an incompatible crossmatch with Bombay phenotype patient

Asian Journal of Transfusion Science
Bombay and para-Bombay are rare phenotypes with H antigen-deficient red blood cells. A 54-year-old male patient suffering from suspected malignant pleural effusion was planned for thoracotomy.
Kella Nivedita, Somnath Mukherjee, Satya Prakash, Ansuman Sahu, Debasish Mishra   +4 more
doaj   +1 more source

A rapid molecular method (polymerase chain reaction with sequence-specific primers) to genotype for ABO blood group and secretor status and its potential for organ transplants

, 1997
We hypothesize that kidneys from non-secretor blood group A2 donors may be used for transplant into non-A recipients. In addition, we believe that organs from A2 donors may be used in non-A recipients where the anti-A titer is low.
Welsh, K.I., Procter, J., Crawford, J., Bunce, M.   +3 more
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

ABO blood group discrepancy - An unexpected news for a known blood group O positive regular blood donor

Indian Journal of Pathology and Microbiology
ABO discrepancies occur when cell and serum blood grouping results do not match, posing a significant risk during transfusions. One rare cause of such discrepancies is the presence of B subgroups, including B3, Bx, Bm, and Bel, which show weak or absent ...
Sumita Pandey, Sayantan Saha, Piyali Dutta, Prasun Bhattacharya   +3 more
doaj   +1 more source

Molecularly confirmed para-Bombay (Ah) secretor phenotype with FUT1 c.328G>A and FUT2 c.357C>T mutations: first case report from India: Para-Bombay Ah secretor phenotype from India

Blood Transfusion
A 35-year-old woman presented with symptoms of anemia and hemoglobin of 5.5 g/dL. The patient's blood sample was subjected to standard serological blood grouping, using both tube and column agglutination techniques. Group I discrepancy was found between cell grouping (O Rh D positive) and serum grouping (A group).
Arivazhagan, Thamizhsurabi, Chada, Tejaswi, Chunchu, Srinivasa Rao, Lokhande, Monali, Devendra, Rati   +4 more
openaire   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Secretor status and ankylosing spondylitis.

, 2016
OBJECTIVE: To assess the genetic association between secretor status and ankylosing spondylitis (AS). METHODS: A restriction digest method for determining secretor status was developed; 166 patients with AS and 216 healthy British white controls were ...

core  

Participant characteristics by child and mother secretor status.

, 2016
Participant characteristics by child and mother secretor status.
Paula Smith-Brown (3127242), Mark Morrison (159827), Peter S. W. Davies (2587675), Lutz Krause (11359)   +3 more
core   +1 more source