Results 81 to 90 of about 546,603 (232)

Association of ABO blood group and secretor phenotype with severe COVID‐19 [PDF]

Transfusion, 2020
Valenti, Luca, Villa, Stefania, Baselli, Guido, Temporiti, Roberta, Bandera, Alessandra, Scudeller, Luigia, Prati, Daniele   +6 more
openaire   +3 more sources

Sequence and expression of a candidate for the human Secretor blood group alpha(1,2)fucosyltransferase gene (FUT2). Homozygosity for an enzyme-inactivating nonsense mutation commonly correlates with the non-secretor phenotype.

The Journal of biological chemistry, 1995
Synthesis of soluble A, B, H, and Lewis b blood group antigens in humans is determined by the Secretor (Se) (FUT2) blood group locus. Genetic, biochemical, and molecular analyses indicate that this locus corresponds to an alpha(1,2)fucosyltransferase gene distinct from the genetically-linked H blood group alpha(1,2)fucosyltransferase locus.
R J, Kelly, S, Rouquier, D, Giorgi, G G, Lennon, J B, Lowe   +4 more
openaire   +2 more sources

Strong but not absolute correlation between the G428A FUT2 nonsense mutation and symptomatic NoV infection.

, 2013
*SeSe and Sese428 vs.
Alberto Arnedo (372844), Rebeca Montava (372837), Reem Abu Mallouh (372839), Elin Kindberg (372833), Ammi Grahn (372841), Lennart Svensson (57397), Marta Fos Lidón (372835), Juan Bellido (372842), Gustaf E. Rydell (372834), Jesús Rodríguez-Díaz (5653837), Göran Larson (372846), Beatrice Carlsson (372832), Javier Buesa (213858)   +12 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

ABH Secretor Status Using Lewis blood type and Saliva Test

, 1994
We studied the ABH secretor status using Lewis blood type and saliva test in 85 patients who underwent septoplasty or intranasal ethmoidectomy.
윤주헌, 이정권
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Detection of a rare subgroup of A phenotype while resolving ABO discrepancy

Asian Journal of Transfusion Science, 2019
Weaker subgroups of ABO blood group system give rise to discrepancies between forward and reverse grouping and cause diagnostic difficulties in routine blood banking.
Revathy Nair, Harita Gogri, Swati Kulkarni, Debasish Gupta   +3 more
doaj   +1 more source

Effect of secretor status on Prevotella abundance.

, 2016
Effect of secretor status on Prevotella abundance.
Paula Smith-Brown (3127242), Mark Morrison (159827), Peter S. W. Davies (2587675), Lutz Krause (11359)   +3 more
core   +1 more source