Results 61 to 70 of about 95,011 (288)

The host immune response to gastrointestinal nematode infection in sheep [PDF]

, 2015
non peer reviewedGastrointestinal nematode infection represents a major threat to the health, welfare and productivity of sheep populations worldwide. Infected lambs have a reduced ability to absorb nutrients from the gastrointestinal tract, resulting in
Abraham, Ahmed, Akiho, Amarante, Andronicos, Anthony, Balic, Balic, Balic, Balic, Becattini, Beraldi, Bishop, Bisset, Bisset, Bowdridge, Brunsdon, Brunsdon, Brunsdon, Buddle, Cardia, Clarke, Conway, Coop, Craig, Craig, Crespo, Dawicki, Deplancke, deSchoolmeester, Diez-Tascon, Donaldson, Douch, Douch, Dunsmore, Else, Finkelman, Finkelman, Finney, French, Fuhrman, Geijtenbeek, Gilfillan, Gill, Glass, Gossner, Gossner, Grainger, Halliday, Hansen, Harriman, Harrison, Harrison, Hassan, Hassan, Henderson, Hogan, Houdijk, Hsieh, Huntley, Huntley, Huntley, Ingham, Khan, Kim, Kooyman, Korn, Lacroux, Lazarevic, Lighvani, MacKinnon, Madden, Malan, Mantovani, Marson, McClure, McGuckin, McKenna, McRae, McSorley, Meeusen, Mori, Nair, Ohkura, Paul, Pernthaner, Pernthaner, Pettit, Rainbird, Rosenberg, Sangster, Scott, Seaton, Shakya, Shaw, Shaw, Smith, Smith, Stear, Stear, Stear, Stear, Stevenson, Stone, Strain, Sutherland, Szabo, Taylor, Terefe, Urb, Vallance, Vignali, Voehringer, Williams   +113 more
core   +1 more source

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source

Features of local immunity of an oral cavity at children with rheumatic diseases [PDF]

Саратовский научно-медицинский журнал, 2011
It is revealed that level decrease slgA at children rheumatic diseases is risk factor of development of plural caries of teeth, and also developments of inflammatory diseases of periodont and an oral cavity mucous membrane. Insufficiency IgAs of a saliva
Kozlitina Y.A. Chugaeva U.Y. Admakin O.I.
doaj  

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

The structure and dynamics of secretory component and its interactions with polymeric immunoglobulins

eLife, 2016
As a first-line vertebrate immune defense, the polymeric immunoglobulin receptor (pIgR) transports polymeric IgA and IgM across epithelia to mucosal secretions, where the cleaved ectodomain (secretory component; SC) becomes a component of secretory ...
Beth M Stadtmueller, Kathryn E Huey-Tubman, Carlos J López, Zhongyu Yang, Wayne L Hubbell, Pamela J Bjorkman   +5 more
doaj   +1 more source

Development of simple detection method of polyreactive secretory immunoglobulin A in saliva

Journal of Physical Fitness and Sports Medicine, 2022
The level of secretory immunoglobulin A (SIgA) in saliva is associated with the risk of upper respiratory infection and has been identified as a condition indicator for athletes and an indicator of mucosal immune function in the elderly.
Ziyue Sun, Yuto Inai, Kyoko Koseki, Satoshi Oikawa, Nobuhiko Eda, Takao Akama   +5 more
doaj   +1 more source

Involution of the mouse mammary gland is associated with an immune cascade and an acute-phase response, involving LBP, CD14 and STAT3 [PDF]

, 2004
INTRODUCTION: Involution of the mammary gland is a complex process of controlled apoptosis and tissue remodelling. The aim of the project was to identify genes that are specifically involved in this process.
Bell, A.K., Davies, C.R., Duffy, M.A., Ferrier, R.K., Gusterson, B.A., Heath, V.J., Morris, J.S., Sandilands, G.P., Stein, T., Weber-Hall, S.J.   +9 more
core  

Donor-strand exchange in chaperone-assisted pilus assembly revealed in atomic detail by molecular dynamics [PDF]

, 2008
Adhesive multi-subunit fibres are assembled on the surface of many pathogenic bacteria via the chaperone-usher pathway. In the periplasm, a chaperone donates a β-strand to a pilus subunit to complement its incomplete immunoglobulin-like fold.
Ashcroft, A.E., Paci, E., Radford, S.E., Rose, R.J., Waksman, G., Welsh, T.S.   +5 more
core   +1 more source

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source

Lactoferrin and free secretory component of human milk inhibit the adhesion of enteropathogenic Escherichia coli to HeLa cells

BMC Microbiology, 2001
Background Diarrhoea caused by Escherichia coli is an important cause of infant morbidity and mortality in developing countries. Enteropathogenic Escherichia coli (EPEC) is considered one of the major causes of diarrhoea in children living in developing ...
Giugliano Loreny, de Araújo Andréa
doaj   +1 more source