Results 41 to 50 of about 3,296 (190)

Proteomics and immunocharacterization of Asian mountain pit viper (Ovophis monticola) venom.

PLoS ONE, 2021
The venomic profile of Asian mountain pit viper Ovophis monticola is clarified in the present study. Using mass spectrometry-based proteomics, 247 different proteins were identified in crude venom of O. monticola found in Thailand.
Siravit Sitprija, Lawan Chanhome, Onrapak Reamtong, Tipparat Thiangtrongjit, Taksa Vasaruchapong, Orawan Khow, Jureeporn Noiphrom, Panithi Laoungbua, Arissara Tubtimyoy, Narongsak Chaiyabutr, Supeecha Kumkate   +10 more
doaj   +1 more source

Characterization Of The Acute Pancreatitis Induced By Secretory Phospholipases A2 In Rats

, 2015
Acute pancreatitis (AP) is an inflammatory disease of the pancreas characterized by local inflammation and extrapancreatic effects such as lung injury.
Esquisatto L.C.M., Giglio J.R., Camargo E.A., Esquisatto M.A., Landucci E.C.T., Ribela M.T.C.P., Cintra A.C., Antunes E.   +7 more
core   +2 more sources

Biochemistry and toxicology of proteins and peptides purified from the venom of Vipera berus berus

Toxicon: X, 2022
The isolation and characterization of individual snake venom components is important for a deeper understanding of the pathophysiology of envenomation and for improving the therapeutic procedures of patients. It also opens possibilities for the discovery
Jüri Siigur, PhD, Ene Siigur, PhD
doaj   +1 more source

Snake Venom Proteomics of Samar Cobra (Naja samarensis) from the Southern Philippines: Short Alpha-Neurotoxins as the Dominant Lethal Component Weakly Cross-Neutralized by the Philippine Cobra Antivenom

Frontiers in Pharmacology, 2021
The Samar Cobra, Naja samarensis, is endemic to the southern Philippines and is a WHO-listed Category 1 venomous snake species of medical importance. Envenomation caused by N.
Praneetha Palasuberniam, Praneetha Palasuberniam, Yi Wei Chan, Kae Yi Tan, Choo Hock Tan   +4 more
doaj   +1 more source

Secretory Phospholipase A2 Enzymes in Acute Lung Injury [PDF]

Cell Biochemistry and Biophysics, 2021
The secretory phospholipase A2 (sPLA2) group of secreted enzymes hydrolyze phospholipids and lead to the production of multiple biologically active lipid mediators. sPLA2s and their products (e.g., eicosanoids) play a significant role in the pathophysiology of various inflammatory diseases, including life-threatening lung disorders such as acute lung ...
Eleftheria Letsiou, Yu Maw Htwe, Steven M. Dudek   +2 more
openaire   +2 more sources

Phospholipases A1

, 2011
Research in the author's laboratory is supported in part by a Wellcome Trust Senior Research Fellowship (067441), and Wellcome Trust project grants (086658 and 093228) and a Wellcome Trust Prize Studentship (G.S.R).Phospholipase A1 (PLA1) is an enzyme ...
Smith, Terry K., Gregory S. Richmond, Terry K. Smith, Richmond, Gregory S.   +3 more
core   +1 more source

Inactivation of secretory phospholipase A2 by ionizing radiation

Biophysical Journal, 1995
The extracellular phospholipase A2s (PLA2) from cobra venom, rattlesnake venom, and porcine pancreas were analyzed by radiation inactivation to determine their functional aggregation states. The analysis was performed in the presence of the protein transferrin at two different concentrations of PLA2: 5 micrograms/ml.
Reynolds, LJ, Kempner, ES, Hughes, LL, Dennis, EA   +3 more
openaire   +4 more sources

Effect Of Crotapotin And Heparin On The Rat Paw Oedema Induced By Different Secretory Phospholipases A2

, 2015
The effects of crotapotin (a non-toxic and non-enzymatic acid polypeptide naturally complexed with phospholipase A2) and heparin on rat paw edema induced by different secretory phospholipases A2 (sPLA2) have been investigated.
Toyama M., Cirino G., Landucci E.C.T., Marangoni S., De Nucci G., Antunes E., Oliveira B.   +6 more
core   +2 more sources

Identification of Two Secreted Phospholipases A2 in Human Epidermis

, 2000
Phospholipases A2 are enzymes that catalyze the release of fatty acids from the sn-2 position of phospholipids. Fatty acids have been suggested to play a key role in the barrier function of the epidermis.
Tarroux, Roger, Ceruti, Isabelle, Charveron, Marie, Simon, Marie-Françoise, Chap, Hugues, Maury, Eric, Redoules, Daniel, Prévost, Marie-Claude   +7 more
core   +1 more source

Hydrolysis of surfactant-associated phosphatidylcholine by mammalian secretory phospholipases A₂

, 1998
Hydrolysis of surfactant-associated phospholipids by secretory phospholipases A2is an important potential mechanism for surfactant dysfunction in inflammatory lung diseases.
Moseley Waite, R. Duncan Hite, Randy B. Jacinto, R. Balasubramanian, David Bass, Michael C. Seeds   +5 more
core   +1 more source