In this study, 3D‐TVS measurements of the uterine junction zone (JZ) in 120 patients showed that a JZmax threshold of ≥ 0.45 cm yielded 77% sensitivity and 89% specificity for adenomyosis diagnosis. Notably, JZ thickness varies minimally with age, demonstrating its stability and excellent diagnostic performance.
Mengyu Li +3 more
wiley +1 more source
Shenqi compound enhances pancreatic β-cell secretion by promoting the maturation and transport of insulin secretory vesicles through the NOD1/RIP2 signaling pathway. [PDF]
Yao N +6 more
europepmc +1 more source
ABSTRACT Rheumatoid arthritis (RA) is a common autoimmune disease, and early diagnosis is critical for effective treatment. This study aims to identify potential biomarkers related to pyroptosis through serum proteomics analysis, offering new insights for the early diagnosis of RA.
Lei Wang +10 more
wiley +1 more source
Redox compartmentalization drives functional heterogeneity of mature insulin secretory vesicles in pancreatic β-cells. [PDF]
Zhuang L +5 more
europepmc +1 more source
Secretory vesicles of immune cells contain only a limited number of interleukin 6 molecules. [PDF]
Verboogen DRJ +3 more
europepmc +1 more source
The Emerging Role of Microbial Extracellular Vesicles in Neuroinflammation and Neurodegeneration
ABSTRACT Neurodegenerative and neuropsychiatric disorders are increasingly viewed as systemic conditions shaped by interactions among peripheral immunity, microbiota, and the central nervous system. However, the mechanisms linking microbial activity to neuroinflammation and neurodegeneration remain poorly defined.
Julio Jesús Estrada‐Valbuena +3 more
wiley +1 more source
Reciprocal regulation between AtFH5-labeled secretory vesicles and PI(4,5)P<sub>2</sub> oscillation at the plasma membrane directs pollen germination. [PDF]
Zhao Y +6 more
europepmc +1 more source
Secretory vesicle protein homologues in choanoflagellates
Regulert vesikeleksocytose, som i tilfellet med høyt spesialisert synaptisk vesikelsekresjon, styres av et sett evolusjonært konserverte proteiner. Mange av disse proteinene er eldre enn dyrene. Målet med denne avhandlingen var å studere opprinnelsen til og evolusjonen av pre-synaptiske proteinkomplekser som er viktige for transmitterfrigjøring ...
openaire +1 more source
ABSTRACT Aims While many patients with lower urinary tract symptoms (LUTS) improve by treating peripheral causes, a substantial proportion continue to experience symptoms despite apparently successful interventions. Central nervous system (CNS) mechanisms could potentially contribute to persisting symptoms after the initial peripheral cause has been ...
Mathijs M. de Rijk +7 more
wiley +1 more source
Feedback inhibition of actin on Rho mediates content release from large secretory vesicles. [PDF]
Segal D +3 more
europepmc +1 more source

