Results 211 to 220 of about 71,348 (257)
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Molecular mechanism of secretory vesicle docking
Biochemical Society Transactions, 2010Docking, the stable association of secretory vesicles with the plasma membrane, is considered to be the necessary first step before vesicles gain fusion-competence, but it is unclear how vesicles dock. In adrenal medullary chromaffin cells, access of secretory vesicles to docking sites is controlled by dense F-actin (filamentous actin) beneath the ...
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Secretory granule and synaptic vesicle formation
Current Opinion in Cell Biology, 1991Sorting of secreted proteins into dense-core secretory granules may involve selective aggregation of regulated secretory proteins, rather than a conventional sortase. Synaptic vesicles, which mediate paracrine communication between adjacent cells, appear to arise by a modification of the early endosome pathway.
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Evidence for anion channels in secretory vesicles
Neuroscience, 1988Secretory vesicles from bovine neurohypophysis were reconstituted into lipid bilayers. Electrical measurements on the lipid bilayers under voltage clamp demonstrated the presence of channels that are permeable to chloride ions, are blocked by 4,4'-diisothiocyanostilbene-2,2'-disulfonate, and are slightly voltage dependent.
E F, Stanley +2 more
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From Nucleus to Secretory Vesicle
Science's STKE, 2003High mobility group protein 1 (HMGB1) is an abundant nuclear protein associated with chromatin that functions in regulating transcription. HMGB1 is also released from necrotic cells, which stimulates inflammatory responses. In some cells, such as monocytes and macrophages, HMGB1 is secreted in response to various stimulating ligands ...
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Probing Single Secretory Vesicles with Capillary Electrophoresis
Science, 1998Secretory vesicles obtained from the atrial gland of the gastropod mollusk Aplysia californica were chemically analyzed individually with a combination of optical trapping, capillary electrophoresis separation, and a laser-induced fluorescence detection.
D T, Chiu +8 more
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Lipids and Secretory Vesicle Exocytosis
2008In recent years, the number of lipids implicated in the regulation of the synaptic vesicle exocytosis has risen dramatically. It is now clear that lipids such as the phosphoinositides, arachidonic acid, lysophospholipids, and cholesterol play a critical regulatory role in the processes leading up to exocytosis.
Meunier, Frederic A., Osborne, Shona L.
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Seminal Vesicles: Development, Secretory Products, and Fertility
Archives of Andrology, 1990The development of the seminal vesicle from the mesonephric duct is described. Particular attention is given to the recent biochemistry of seminal vesicle proteins. Proteins in the seminal vesicle fluid are few in number, may be insoluble at certain pH, and frequently form large macromolecular aggregates.
P T, Curry, R W, Atherton
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1996
Abstract Vesicle-mediated secretion from animal cells utilizes three types of secretory vesicles (1, 2) (Fig. 1). The first type is the constitutive secretory vesicle (CSV), which is thought to be common to all eukaryotic cells and which mediates the continuous secretion of newly synthesized proteins.
Masato ohashi +2 more
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Abstract Vesicle-mediated secretion from animal cells utilizes three types of secretory vesicles (1, 2) (Fig. 1). The first type is the constitutive secretory vesicle (CSV), which is thought to be common to all eukaryotic cells and which mediates the continuous secretion of newly synthesized proteins.
Masato ohashi +2 more
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Secretory Vesicle Swelling by Atomic Force Microscopy
2006The swelling of secretory vesicles has been implicated in exocytosis, but the underlying mechanism of vesicle swelling remained unknown. Earlier studies from our laboratory demonstrated the association of the alpha-subunit of heterotrimeric GTP-binding protein G(alphai3) with zymogen granule membrane and implicated its involvement in vesicle swelling ...
Sang-Joon, Cho, Bhanu P, Jena
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Proteomic analysis of a developmentally regulated secretory vesicle
PROTEOMICS, 2001Secretion of spore coat proteins from the prespore secretory vesicles (PSVs) in Dictyostelium discoideum is a signal mediated event that underlies terminal cell differentiation, and represents an important case of developmentally regulated secretion.
S, Srinivasan +7 more
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