Results 71 to 80 of about 129,831 (277)

Beltrami-Meusnier formulas of generalized semi ruled surfaces in semi Euclidean space

Kuwait Journal of Science, 2014
In this paper, we study the sectional curvatures of the generalized semi ruled surfaces in semi Euclidean space   The first fundamental form and the metric coefficients of the generalized semi ruled surfaces are calculated and in these regards ...
MAHMUT AKYIG١IT, SOLEY ERSOY, MURAT TOSUN   +2 more
doaj  

On projectivized vector bundles and positive holomorphic sectional curvature

, 2016
We generalize a construction of Hitchin to prove that, given any compact K\"ahler manifold $M$ with positive holomorphic sectional curvature and any holomorphic vector bundle $E$ over $M$, the projectivized vector bundle ${\mathbb P}(E)$ admits a K ...
Alvarez, Angelynn, Heier, Gordon, Zheng, Fangyang   +2 more
core  

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Generalized pseudo Ricci symmetric manifolds with semi-symmetric metric connection

Kuwait Journal of Science, 2014
In this paper, firstly an example of a manifold with almost constant curvature and nearly quasi constant curvature which is neither quasi Einstein nor nearly quasi Einstein is given.
SEZGIN ALTAY DEMIRBAG
doaj  

Contravariant Curvatures of Doubly Warped Product Poisson Manifolds

Mathematics
In this paper, we investigate the sectional contravariant curvature of a doubly warped product manifold ( fB×bF,g˜,Π=ΠB+ΠF) equipped with a product Poisson structure Π, using warping functions and sectional curvatures of its factor manifolds (B,g˜B,ΠB ...
Foued Aloui, Shyamal Kumar Hui, Ibrahim Al-Dayel   +2 more
doaj   +1 more source

A Liouville Property of Holomorphic Maps

The Scientific World Journal, 2013
We prove a Liouville property of holomorphic maps from a complete Kähler manifold with nonnegative holomorphic bisectional curvature to a complete simply connected Kähler manifold with a certain assumption on the sectional curvature.
Chengjie Yu
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Curvature of a class of indefinite globally framed $f$-manifolds

, 2008
We present a compared analysis of some properties of indefinite almost $\mathcal{S}$-manifolds and indefinite $\mathcal{S}$-manifolds. We give some characterizations in terms of the Levi-Civita connection and of the characteristic vector fields. We study
Brunetti, Letizia, Pastore, Anna Maria
core   +2 more sources

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source