Results 111 to 120 of about 20,950 (257)

Secukinumab May Be an Effective Treatment Option for Axial Spondyloarthritis and Psoriatic Arthritis Patients with a History of Malignancy: Multicenter Real-Life Experience from Turkey

Journal of Clinical Medicine
Background: Secukinumab is a monoclonal antibody against interleukin 17 approved for patients with axial spondyloarthritis (axSpA), psoriatic arthritis (PsA), and psoriasis.
Tuğba Ocak, B. Yağız, B. Ocak, Özge Yoğurtçu, Fatma Başıbüyük, Dilek Tezcan, S. Ermurat, Elif İnanç, Gülşah Yamancan, Fatih Albayrak, R. Sagir, Ayşe Nur Bayındır Akbaş, Osman Cüre, B. N. Coşkun, S. Yolbaş, Uğur Karasu, B. Kısacık, S. Koca, Ismail Sari, S. Akar, E. Dalkılıç, Yavuz Pehlivan   +21 more
semanticscholar   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Long-term data on sirolimus treatment in lupus nephritis patients [PDF]

, 2017
Poster Session: New therapies and therapeutic targets – SLE: abstract no ...
Chan, DTM, Chan, GC, Kwan, LP, Ma, MK, Mok, MM, Yap, YHD   +5 more
core   +1 more source

Secukinumab in the Treatment of Psoriasis: A Narrative Review on Early Treatment and Real-World Evidence

Dermatologic Therapy
Psoriasis is a chronic, immune-mediated, inflammatory skin disease, associated with multiple comorbidities and psychological and psychiatric disorders. The quality of life of patients with this disease is severely compromised, especially in moderate-to ...
P. Malagoli, P. Dapavo, P. Amerio, L. Atzori, A. Balato, F. Bardazzi, L. Bianchi, Angelo Cattaneo, A. Chiricozzi, M. Congedo, M. Fargnoli, C. Giofré, P. Gisondi, C. Guarneri, S. Lembo, F. Loconsole, G. Mazzocchetti, S. Mercuri, Pietro Morrone, A. Offidani, Giovanni Palazzo, A. Parodi, G. Pellacani, Stefano Piaserico, C. Potenza, F. Prignano, M. Romanelli, Paola Savoia, L. Stingeni, M. Travaglini, E. Trovato, M. Venturini, L. Zichichi, Antonio Costanzo   +33 more
semanticscholar   +1 more source

Treating to Target in Hidradenitis Suppurativa: Canadian Perspectives

JEADV Clinical Practice, EarlyView.
Wayne Gulliver, Irina Turchin, Tracey Brown‐Maher, Marni Wiseman, Lauren Lam, Jessica Asgarpour, Raed Alhusayen   +6 more
wiley   +1 more source

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source

Acrodermatitis continua of Hallopeau: clinical perspectives. [PDF]

, 2019
Acrodermatitis continua of Hallopeau (ACH) is a rare, sterile pustular eruption of one or more digits. The condition presents with tender pustules and underlying erythema on the tip of a digit, more frequently arising on a finger than a toe.
Beck, Kristen M, Bhutani, Tina, Liao, Wilson, Ly, Karen, Smith, Mary Patricia, Thibodeaux, Quinn   +5 more
core  

Four-year real-world experience of secukinumab in a large Italian cohort of axial spondyloarthritis

Frontiers in Immunology
Objectives This study aims to evaluate in a real-life Italian multicenter cohort of axial spondyloarthritis (axSpA) (1) the 4-year effectiveness and safety of secukinumab, (2) the drug retention rate (DRR), and (3) the impact of the line of bDMARDs ...
R. Ramonda, M. Lorenzin, M. Chimenti, S. D’Angelo, A. Marchesoni, C. Selmi, E. Lubrano, Leonardo Santo, M. M. Luchetti Gentiloni, Fabiola Atzeni, Alberto Cauli, Maria Manara, Maurizio Rossini, R. Foti, G. Cozzi, L. Scagnellato, M. Ferraioli, Antonio Carriero, Nicoletta Luciano, Francesca Ruzzon, M. Fatica, E. Fracassi, Andrea Doria, Rosario Foti, A. Carletto   +24 more
semanticscholar   +1 more source

Evidence‐Based and Consensus‐Based Approach to the Treatment of Hidradenitis Suppurativa: Based on the Updated European SK2 Guidelines for the Treatment of Hidradenitis Suppurativa/Acne Inversa

JEADV Clinical Practice, EarlyView.
Wayne P. Gulliver
wiley   +1 more source

Economic burden of hidradenitis suppurativa based on healthcare resource utilization: German claims data analysis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Hidradenitis suppurativa (HS) is a chronic, debilitating skin disease affecting approximately 0.1% of the German population. Patients with HS require substantial healthcare resource utilization. This study aimed to assess the economic burden associated with HS in Germany.
Falk G. Bechara, Tanja Tran, Sandeep Kiri, Romy Bley, Kathrin Schlüter, Claudia Grellmann, Sima Melnik, Sylke Schneider‐Burrus   +7 more
wiley   +1 more source