Results 121 to 130 of about 388,946 (338)

An Electronic Delphi Study to Establish Pediatric Intensive Care Nursing Research Priorities in Twenty European Countries* [PDF]

, 2014
OBJECTIVES:: To identify and to establish research priorities for pediatric intensive care nursing science across Europe. DESIGN:: A modified three-round electronic Delphi technique was applied.
Latour, Jos M., Tume, Lyvonne Nicole, van den Hoogen, Agnes, Wielenga, Joke M.   +3 more
core   +3 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Sedation Monitoring and Management during Percutaneous Endoscopic Lumbar Discectomy

Case Reports in Anesthesiology, 2016
Percutaneous endoscopic laser discectomy (PELD) is a painful intervention that requires deep sedation and analgesia. However, sedation should be light at some point because cooperation by the patient during the procedure is required for successful ...
Menekse Oksar, Tulin Gumus, Orhan Kanbak
doaj   +1 more source

ELECTRICAL ACTIVITY OF THE HUMAN BRAIN DURING ARTIFICIAL SLEEP: 2. REGIONAL DIFFERENTIATION OF RESPONSE TO BARBITURATE SEDATION [PDF]

, 1951
B. D. Wyke
openalex   +1 more source

Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness [PDF]

, 2018
BACKGROUND: There are conflicting data on the effects of antipsychotic medications on delirium in patients in the intensive care unit (ICU). METHODS: In a randomized, double-blind, placebo-controlled trial, we assigned patients with acute ...
Bernard, G.R., Boehm, L.M., Bowton, D.L., Brummel, N.E., Carson, S.S., Chandrasekhar, R., Dittus, R.S., Douglas, I.S., Ely, E.W., Exline, M.C., Feinstein, D.J., Girard, T.D., Gong, M.N., Hite, R.D., Hough, C.L., Hughes, C.G., Hyzy, R.C., Jackson, J.C., Khan, B., Malhotra, A., Masica, A.L., Owens, R.L., Pandharipande, P.P., Patel, M.B., Pisani, M.A., Pun, B.T., Rock, P., Schmidt, G.A., Schweickert, W.D., Stollings, J.L., Strength, C., Thompson, J.L.   +31 more
core   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

PREANESTHETIC SEDATION AND ANALGESIA FOR INTRAOCULAR OPERATIONS DONE WITH LOCAL ANESTHESIA [PDF]

, 1953
W. S. ATKINSON
openalex   +1 more source

Dexmedetomidine vs propofol-remifentanil conscious sedation for awake craniotomy: a prospective randomized controlled trial.

British Journal of Anaesthesia, 2016
BACKGROUND Awake craniotomy (AC) is performed for the resection of brain tumours in close proximity to areas of eloquent brain function to maximize reduction of tumour mass and minimize neurological injury.
Nicolai Goettel, Nicolai Goettel, S. Bharadwaj, L. Venkatraghavan, J. Mehta, M. Bernstein, P. Manninen   +6 more
semanticscholar   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Risk factors for chloral hydrate sedation failure in pediatric patients: a retrospective analysis [PDF]

Korean Journal of Anesthesiology
Background This study aimed to investigate the risk factors for chloral hydrate sedation failure and complications in a tertiary children’s hospital in South Korea.
Young-Eun Jang, Jung-Bin Park, Pyoyoon Kang, Sang-Hwan Ji, Eun-Hee Kim, Ji-Hyun Lee, Hee-Soo Kim, Jin-Tae Kim   +7 more
doaj   +1 more source