Possible proteomic biomarkers for the detection of pancreatic cancer in oral fluids
The 80% mortality rate of pancreatic-cancer (PC) makes early diagnosis a challenge. Oral fluids (OF) may be considered the ultimate body fluid for non-invasive examinations.
O. Deutsch+11 more
doaj +1 more source
Pediatric Procedural Sedation in the Emergency Setting
Background:. Pediatric emergency department (ED) visits are common. Many are due to injury, which require procedural treatments with sedation. There are many well researched independent predictors of adverse events for pediatric procedural sedation.
Elizabeth A. Lucich, MD+4 more
doaj +1 more source
Antiepileptic drugs’ tolerability and safety – a systematic review and meta-analysis of adverse effects in dogs [PDF]
Various anti-epileptic drugs (AEDs) are used for the management of idiopathic epilepsy (IE) in dogs. Their safety profile is an important consideration for regulatory bodies, owners and prescribing clinicians.
A Stabile+105 more
core +3 more sources
Crossed modules, double group-groupoids and crossed squares [PDF]
In this paper using split extensions of group-groupoids we obtain the notion of crossed modules over group-grouoids which are also called 2-groups and we prove a categorical equivalence of these types of crossed modules and double group-groupoids which are internal to the category of group-groupoids. This equivalence enables us to produce more examples
arxiv +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Korean clinical practice guidelines for diagnostic and procedural sedation [PDF]
Safe and effective sedation depends on various factors, such as the choice of sedatives, sedation techniques used, experience of the sedation provider, degree of sedation-related education and training, equipment and healthcare worker availability, the ...
Sang-Hyun Kim+18 more
doaj +1 more source
Use of volatile agents for sedation in the intensive care unit: A national survey in France.
BackgroundCurrent intensive care unit (ICU) sedation guidelines recommend strategies using non-benzodiazepine sedatives. This survey was undertaken to explore inhaled ICU sedation practice in France.MethodsIn this national survey, medical directors of ...
Raiko Blondonnet+10 more
doaj +1 more source
Quality of colonoscopy in an organised colorectal cancer screening programme with immunochemical faecal occult blood test. The EQuIPE study (Evaluating Quality Indicators of the Performance of Endoscopy) [PDF]
OBJECTIVES: To assess variation in the main colonoscopy quality indicators in organised colorectal cancer (CRC) screening programmes based on faecal immunochemical test (FIT).
Alessandra Barca+15 more
core +1 more source
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang+9 more
wiley +1 more source
Orofacial Migraine and Neurovascular Orofacial Pain: Response to Treatment—A Pilot Study
Introduction: The International Classification of Orofacial Pain (ICOP) recognizes orofacial migraine (OFM) and neurovascular orofacial pain (NVOP) as migraine-related entities affecting the facial and oral regions.
Rafael Benoliel+3 more
doaj +1 more source