Results 61 to 70 of about 318,233 (338)
Factors associated with the efficacy of polyp detection during routine flexible sigmoidoscopy [PDF]
, 2017 Objective: Flexible sigmoidoscopy reduces the incidence of colonic cancer through the detection and removal of premalignant adenomas. However, the efficacy of the procedure is variable.
Anderson, John H. +4 more
core +1 more source
Moderate sedation with single-dose remimazolam tosilate in elderly male patients undergoing transurethral resection of the prostate with spinal anesthesia: a prospective, single-arm, single-centre clinical trial [PDF]
, 2022 Tang‐yuan‐meng Zhao +6 more
openalex +1 more source
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Alteration of coupling between brain and heart induced by sedation with propofol and midazolam.
PLoS ONE, 2019 For a comprehensive understanding of the nervous system, several previous studies have examined the network connections between the brain and the heart in diverse conditions. In this study, we identified coupling between the brain and the heart along the
Dong-Ok Won +4 more
doaj +1 more source
Jurnal Riset Kesehatan, 2017 Sedation is an important factor to improve patient comfort. Over sedation may lead to a longer ventilator time. To prevent over sedation need an instrument can measure accurately the status of sedation. This study aimed to analyze the differences between
Hellena Deli +2 more
doaj +1 more source
Annals of Thoracic Medicine, 2023 BACKGROUND: Sedation is fundamental to the management of patients in the intensive care unit (ICU). Its indications in the ICU are vast, including the facilitating of mechanical ventilation, permitting invasive procedures, and managing anxiety and ...
Zohair Al Aseri +5 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Procedural Sedation and Analgesia in Children: Perspectives from Paediatric Emergency Physicians
Proceedings of Singapore Healthcare, 2010 Procedural sedation and analgesia in children is now widely practised in many emergency departments internationally. In this article, we address the general principles, indications, guidelines, medications, adverse events and future research in ...
Lai Peng Tham MBBS, MMed (Paediatrics) +1 more
doaj +1 more source
Use of volatile agents for sedation in the intensive care unit: A national survey in France.
PLoS ONE, 2021 BackgroundCurrent intensive care unit (ICU) sedation guidelines recommend strategies using non-benzodiazepine sedatives. This survey was undertaken to explore inhaled ICU sedation practice in France.MethodsIn this national survey, medical directors of ...
Raiko Blondonnet +10 more
doaj +1 more source