Results 11 to 20 of about 49,112 (154)

Prospective audit of sedation/anesthesia practices for children undergoing computerized tomography in a tertiary care institute

Journal of Anaesthesiology Clinical Pharmacology, 2020
Background and Aims: The aim of the study was to enumerate the sedative drugs used, assess the efficacy of sedative drugs, and determine the incidence of adverse events.
Aakriti Gupta, Indu Sen, Neerja Bhardwaj, Sandhya Yaddanapudi, Preethy J Mathew, Neeru Sahni, Anmol Bhatia   +6 more
doaj   +1 more source

Evaluating different sedative drugs applied in procedural sedation [PDF]

Reviews in Clinical Medicine, 2015
There are various criteria that affect the efficacy of the procedural sedation strategies required for performing different processes in emergency departments.
Azadeh Tafakori, Mohammad Gharavifard, Hamid Zamani   +2 more
doaj   +1 more source

Causative drugs for drug-induced cutaneous reactions in central China: a 608-case analysis, [PDF]

Anais Brasileiros de Dermatologia, 2020
Background: Reports regarding the causative drugs of drug-induced cutaneous adverse reactions in China are indistinct, such that different regions have reported the spectrum of drugs differs substantially in different clinical conditions.
Jun Zhao, Lei Hu, Lihua Zhang, Maosong Zhou, Lichen Gao, Lin Cheng   +5 more
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The impact of sedative and vasopressor agents on cerebrovascular reactivity in severe traumatic brain injury

Intensive Care Medicine Experimental, 2023
Background The aim of this study is to evaluate the impact of commonly administered sedatives (Propofol, Alfentanil, Fentanyl, and Midazolam) and vasopressor (Dobutamine, Ephedrine, Noradrenaline and Vasopressin) agents on cerebrovascular reactivity in ...
Logan Froese, Emma Hammarlund, Cecilia A. I. Åkerlund, Jonathan Tjerkaski, Erik Hong, Caroline Lindblad, David W. Nelson, Eric P. Thelin, Frederick A. Zeiler   +8 more
doaj   +1 more source

Effect of combined sedation using multiple drugs on inflammatory cytokines in patients with acute respiratory distress syndrome

Brazilian Journal of Pharmaceutical Sciences, 2023
The innate immune response plays an important role in the pathophysiology of acute respiratory distress syndrome (ARDS); however, no drug has been proven to be beneficial in the management of ARDS.
Xiangbi Nie, Liqiong Lou, Hui Xu, Wei Xiong, Zenggeng Wang   +4 more
doaj   +1 more source

Temporal relationship between vasopressor and sedative administration and cerebrovascular response in traumatic brain injury: a time-series analysis

Intensive Care Medicine Experimental, 2023
Background Although vasopressor and sedative agents are commonly used within the intensive care unit to mediate systemic and cerebral physiology, the full impact such agents have on cerebrovascular reactivity remains unclear.
Logan Froese, Alwyn Gomez, Amanjyot Singh Sainbhi, Nuray Vakitbilir, Izabella Marquez, Fiorella Amenta, Kevin Y. Stein, Frederick A. Zeiler   +7 more
doaj   +1 more source

Sedation, Analgesia, and Muscle Relaxation During VV-ECMO Therapy in Patients With Severe Acute Respiratory Syndrome Coronavirus Type 2 (SARS-CoV-2): A Single-Center, Retrospective, Observational Study

Frontiers in Medicine, 2021
Objective: The pharmacokinetics and pharmacodynamics of ECMO-supported sedative, analgesic, and muscle relaxants have changed, but there are insufficient data to determine the optimal dosing strategies for these agents.
Fang Wu, Mingna Li, Zhongwei Zhang, Jiawei Shang, Yong Guo, Yingchuan Li   +5 more
doaj   +1 more source

Drug Repurposing: The Mechanisms and Signaling Pathways of Anti-Cancer Effects of Anesthetics

Biomedicines, 2022
Cancer is one of the leading causes of death worldwide. There are only limited treatment strategies that can be applied to treat cancer, including surgical resection, chemotherapy, and radiotherapy, but these have only limited effectiveness. Developing a
King-Chuen Wu, Kai-Sheng Liao, Li-Ren Yeh, Yang-Kao Wang   +3 more
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In vivo analgesic, anti-inflammatory, and sedative activity and a molecular docking study of dinaphthodiospyrol G isolated from Diospyros lotus

BMC Complementary Medicine and Therapies, 2020
Background Analgesic, anti-inflammatory, and sedative drugs are available with potential side effects such as peptic ulcer and addiction among other things.
Abdur Rauf, Tareq Abu-Izneid, Fahad A. Alhumaydhi, Naveed Muhammad, Abdullah S. M. Aljohani, Saima Naz, Saud Bawazeer, Abdul Wadood, Mohammad S. Mubarak   +8 more
doaj   +1 more source

Sedation: A Non-Specific Phenomenon

Psychiatry and Clinical Psychopharmacology, 2021
Sedative molecules are defined as substances that decrease, often in correspondence to dose increase, psychomotor performances in animals as well as in humans. These substances are psychotropic drugs that belong to the hypnotic, neuroleptic, anxiolytic,
Michel Bourin, Pharm. D., J. P. David B. Sc., Brid. Àiene. Nic Dhonnchadha   +3 more
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