Results 51 to 60 of about 1,433,306 (343)

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Bioavailability of pesticides in freshwater sediments [PDF]

, 2007
In ecological risk assessment standardized sediment toxicity tests are used to predict the hazard of chemicals for sediment-living organisms. Feeding is a prerequisite in these long-term tests to avoid starvation of test organisms.
Åkerblom, Nina
core  

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Dynamics of rainfall, discharge, suspended sediment and micropollutant transport in the Moselle River, Central Europe

Environmental Sciences Europe
Background Heavy rainfall causes not only high water levels and discharge but can also lead to the mobilization of sediments and pollutants to rivers. In contrast, droughts with low discharge can impair water quality due to minimized dilution.
Magdalena Uber, Liza-Marie Beckers, Simon Terweh, Peer Helmke, Thomas Hoffmann   +4 more
doaj   +1 more source

Application and evaluation of sediment fingerprinting techniques in the Manawatu River catchment, New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Geography at Massey University, Palmerston North, New Zealand [PDF]

, 2016
Suspended sediment is an important component of the fluvial environment, contributing not only to the physical form, but also the chemical and ecological character of river channels and adjacent floodplains.
Vale, Simon
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Comprehensive evaluation of water resources security in the Yellow River basin based on a fuzzy multi-attribute decision analysis approach [PDF]

Hydrology and Earth System Sciences, 2014
In this paper, a fuzzy multi-attribute decision analysis approach (FMADAA) was developed for supporting the evaluation of water resources security in nine provinces within the Yellow River basin. A numerical approximation system and a modified left–right
K. K. Liu, C. H. Li, Y. P. Cai, M. Xu, X. H. Xia   +4 more
doaj   +1 more source

Ecological Water Requirement Accounting of the Main Stream of the Yellow River From the Perspective of Habitat Conservation

Frontiers in Ecology and Evolution, 2022
The Yellow River Basin is of great significance to China’s economic and social development and ecological security. The Yellow River Basin is not only an important ecological barrier but also an important economic zone.
Fen Zhao, Fen Zhao, Chunhui Li, Wenxiu Shang, Xiaokang Zheng, Xuan Wang, Qiang Liu, Jiuhe Bu   +7 more
doaj   +1 more source

Analytical Ultracentrifugation: Sedimentation Velocity and Sedimentation Equilibrium [PDF]

, 2008
Analytical ultracentrifugation (AUC) is a versatile and powerful method for the quantitative analysis of macromolecules in solution. AUC has broad applications for the study of biomacromolecules in a wide range of solvents and over a wide range of solute concentrations. Three optical systems are available for the analytical ultracentrifuge (absorbance,
Cole, James L., Lary, Jeffrey W., Moody, Thomas P., Laue, Thomas M.   +3 more
openaire   +3 more sources