Results 71 to 80 of about 152,066 (306)

Is the critical Shields stress for incipient sediment motion dependent on channel-bed slope? [PDF]

open access: yes, 2008
Data from laboratory flumes and natural streams show that the critical Shields stress for initial sediment motion increases with channel slope, which indicates that particles of the same size are more stable on steeper slopes.
Dietrich, William E.   +2 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Sediment Load under Waves and Currents

open access: yesCoastal Engineering 1978, 1978
A technique is proposed for calculating sediment load, the mass concentration of sediment in motion, under combinations of waves and currents. The technique is based on the unidirectional flow method of Ackers and White, Ref. 1. The calibration of the technique against measurements of sediment load under waves has only just begun.
openaire   +2 more sources

This Is Not a Myeloproliferative Neoplasm…

open access: yes
Pediatric Blood &Cancer, EarlyView.
Stephanie Juané Kennedy
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Toward sustainable management: 2D modelling of a self-cleaning system to improve geometry in front of the flushing gate [PDF]

open access: yes, 2018
This paper aims to show how numerical modelling based on 2D SWE can be used to analyze the cleaning effectiveness of flushing waves in storm tanks.
Choi, Gyewoon   +4 more
core   +4 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Lecture notes on sediment transportation and channel stability [PDF]

open access: yes, 1961
These notes have been prepared for a series of lectures on sediment transportation and channel stability given by the authors to a group of engineers and geologists of the U. S. Department of Agriculture assembled at Caltech on September 12-16,1960. The
Brooks, Norman H.   +2 more
core   +1 more source

Estimation of Suspended Sediment Loads Using Copula Functions [PDF]

open access: yesWater, 2017
Suspended sediment load (SSL) observations are usually less frequent than precipitation and river discharge measurements; therefore a reliable procedure is needed for the estimation of SSL. One year of precipitation, SSL, and discharge measurements at 20-min intervals were performed at the Kuzlovec torrent in Slovenia.
Nejc Bezak   +4 more
openaire   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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