Results 91 to 100 of about 152,066 (306)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
, 2009 Much of our knowledge of hydrate distribution in the subsurface comes frominterpretations of remote seismic measurements. A key step in such interpretations isan effective medium theory that relates the seismic properties of a given sediment toits ...
Chand, S., Minshull, T.A.
core
, 2016 In gravel-bed rivers, bedload transport exhibits considerable variability in time and space. Recently, stochastic bedload transport theories have been developed to address the mechanisms and effects of bedload transport fluctuations.
Ancey, C., Bohorquez, P., Heyman, J.
core +3 more sources
Numerical modelling of erosion and sedimentation around offshore pipelines [PDF]
, 1990 In this paper a numerical model is presented for the description of the erosion and sedimentation near pipelines on the sea bottom. The model is based on the Navier-Stokes equations and the equation of motion and continuity of sediment.\ud \ud The ...
Beek, F.A. van, Wind, H.G.
core +3 more sources
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Traumatic Microhemorrhages Are Not Synonymous With Axonal Injury
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Diffuse axonal injury (DAI) is caused by acceleration‐deceleration forces during trauma that shear white matter tracts. Susceptibility‐weighted MRI (SWI) identifies microbleeds that are considered the radiologic hallmark of DAI and are used in clinical prognostication.
Karinn Sytsma +9 more
wiley +1 more source
California coast nearshore processes study [PDF]
The author has identified the following significant results. Large scale sediment plumes from intermittent streams and rivers form detectable seasonal patterns on ERTS-1 imagery.
Pirie, D. M., Steller, D. D.
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Controls on spatial and temporal variations in sand delivery to salmonid spawning riffles [PDF]
, 2017 Fine sediment infiltration into gravel interstices is known to be detrimental to incubating salmonid embryos. Infiltration into spawning riffles can show large spatial variations at the scale of a morphological unit and over time, with significant ...
Milan, David
core +1 more source
Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The role of inflammation in cortical superficial siderosis (cSS), a marker of cerebral amyloid angiopathy (CAA) linked to high hemorrhage risk, is unclear. We examined 15 patients with cSS using 3 T post‐contrast vessel wall MRI (VWI) and CSF analysis.
Philipp Arndt +8 more
wiley +1 more source