Sediment transport capacity response to variations in water discharge in pressurized subglacial channels [PDF]
The CryosphereSediment transport capacity in both subaerial and subglacial channels depends on the shear stress exerted across the channel bottom, which varies with water velocity and channel width.
I. Delaney +6 more
doaj +1 more source
On extracting sediment transport information from measurements of luminescence in river sediment [PDF]
, 2016 Accurately quantifying sediment transport rates in rivers remains an important goal for geomorphologists, hydraulic engineers, and environmental scientists.
Gray, H.J. +4 more
core +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Dynamic Characteristics of Suspended Load and Bed Load Transport in Meltwater Runoff of Qiyi Glacier
Shuitu Baochi Xuebao[Objective] The transportation of sediment via glacial meltwater can not only reflect the glacial erosion and landform evolution, but also is one of the important sediment sources for the downstream river.
ZHAO Yi +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Challenges in transferring knowledge between scales in coastal sediment dynamics
Frontiers in Marine Science, 2015 ‘Packaging’ coastal sediment transport into discrete temporal and spatial scale bands is necessary for measurement programs, modelling, and design. However, determining how to best measure and parameterize information, to transfer between scales, is not ...
Shari L Gallop +15 more
doaj +1 more source
Seasonal sediment dynamics on the Barcelona inner shelf (NW Mediterranean): a small Mediterranean river- and wave-dominated system [PDF]
, 2017 The seasonal pattern of sediment dynamics on an inner shelf characterized by the presence of sediment delivered by a small, mountainous river (with a “flash-flood” regime) was investigated. Near-bottom suspended sediment fluxes across the shelf (i.e. 20,
Grifoll Colls, Manel +3 more
core +2 more sources
Sediment transport‐based metrics of wetland stability
, 2015 Despite the importance of sediment availability on wetland stability, vulnerability assessments seldom consider spatiotemporal variability of sediment transport.
N. Ganju +5 more
semanticscholar +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Mean and fluctuating suspended sediment concentration measurements using ADV [PDF]
, 2012 The present experimental research looks for ways to improve fine sediment transport measurements with ADV by further investigating the factors influencing the backscatter intensity of the acoustic wave.
De Mulder, Tom +2 more
core +1 more source