Results 71 to 80 of about 606,049 (285)

Nitrogen removal in maturation WSP ponds via biological uptake and sedimentation of dead biomass [PDF]

, 2009
In this work a set of experiments was undertaken in a pilot-scale WSP system to determine the importance of organic nitrogen sedimentation on ammonium and total nitrogen removals in maturation ponds and its seasonal variation under British weather ...
Camargo Valero, M.A., Mara, D.D., Newton, R.J.   +2 more
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

A study of a quasilinear model of the particles of a suspension that are aggregated and settled in an inhomogeneous field

Visnik Harkivsʹkogo Nacionalʹnogo Universitetu im. V.N. Karazina. Cepiâ Matematika, Prikladna Matematika i Mehanika, 2020
The mathematical model of the sedimentation process of suspension particles is usually a quasilinear hyperbolic system of partial differential equations, supplemented by initial and boundary conditions.
Natalya Kizilova, Sergii Poslavskyi, Vitaliia Baranets   +2 more
doaj   +1 more source

Deep Sea Sedimentation

Environmental Health Perspectives, 1974
An important problem in the study of microparticles in the marine environment, suspended in the water column or deposited as sediment on the ocean bottom, is the determination of provenance of the microparticles-where did they come from and by what processes were they transported to the sampling location?
openaire   +2 more sources

Understanding and Finding Solutions to the Problem of Sedimentation in the National Wildlife Refuge System [PDF]

, 2017
The National Wildlife Refuge System (Refuge System) is a collection of public lands maintained by the U.S. Fish and Wildlife Service for migratory birds and other wildlife.
Eash, Josh D., Jenni, Karen E., Knutsen, Gregory A., Nieman, Timothy L., Post van der Burg, Max   +4 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

An Estimation Method of River Dry Runoff Alteration after Upper New Reservoirs Storage

Applied Sciences
The impact of reservoirs on downstream river hydrological characteristics is always a focal point in relevant studies exploring the relationship between rivers and dams. Anticipating river runoff patterns following the construction of new dams is crucial
Zuoqiang Chen, Ya Deng, Aixing Ma, Ying Hu, Jiashi Li, Lingqi Li   +5 more
doaj   +1 more source

Dynamical demixing of a binary mixture under sedimentation

, 2018
We investigate the sedimentation dynamics of a binary mixture, the species of which differ by their Stokes coefficients but are identical otherwise. We analyze the sedimentation dynamics and the morphology of the final deposits using Brownian dynamics ...
Araujo, N. A. M., Braz, V. C., da Gama, M. M. Telo, Nunes, A. S.   +3 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source