Results 81 to 90 of about 48,635 (253)

Enzyme activity and seedling growth of soybean seeds under accelerated aging [PDF]

Journal of Stress Physiology & Biochemistry, 2013
Seed aging is the main problem of seed storage. Changes of bio-chemical and reduction of seedling growth are consequence of seed deterioration. An experiment was conducted to evaluate the effects of accelerated aging on soybean seed germination indexes
Yadollhhi Nooshabadi S.J., Mashayekhi F.
doaj  

Effect of Seed Priming on Seed Germination and Vigour in Fresh and Aged Seeds of Cucumber

International Journal of Environment, Agriculture and Biotechnology, 2017
Seed priming (seed invigouration) has gained a lot of importance in recent times as it emerged as a most promising area of seed quality enhancement technique. Priming is a pre-sowing treatment, that involves exposure of seeds to a low external water potential that limits hydration,(controlled hydration of seed) to a level that permits pre-germinative ...
Pratima Pandey, K Bhanuprakash, Umesh Umesh   +2 more
openaire   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Effects of melatonin and tryptophan applications on viability and germination performance of tomato seeds during and after artificial aging

Acta Scientiarum Polonorum: Hortorum Cultus
Although the diurnal fluctuations of melatonin (Mel) content in plants and its role in abiotic and biotic stress tolerance are well-documented, little is known about its changes within seeds and its potential effects on seed viability or the aging ...
Aygül Karaca, Ahmet Korkmaz
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Identification of Genes for Rice Seed Storability and Transcriptome Analysis Under Different Aging Conditions [PDF]

中国水稻科学
【Objective】Seed storability is crucial for germplasm conservation, food security, and sustainable development. This study aims to identify QTLs associated with rice seed storability and explore the genetic basis of seed storability under different aging ...
LIAO Zhengming, GUO Liang, PAN Xiaowu, LI Yongchao, DONG Zheng, LI Xiaoxiang
doaj   +1 more source

Aging Story of Seeds: The Science behind Seed Deterioration

Journal of Advances in Biology & Biotechnology
The aging process possess significant challenge to preserve seed integrity and germination capacity under storage. The aging process triggers substantial changes that impact their quality and longevity of seeds. Accelerated aging is a seed vigour test where short-term exposure to high temperature and humidity induces rapid deterioration.
Arivusudar S., Vidya Theertha V.P., Nivedhitha M.S., Beena R.   +3 more
openaire   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source