A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol +18 more
wiley +1 more source
Visible-Near-Infrared Hyperspectral Imaging Enables Nondestructive Identification of Bean Accessions via 1D Spectral Reflectance Analysis. [PDF]
Falcioni R +5 more
europepmc +1 more source
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui +14 more
wiley +1 more source
Application of seed micromorphology in taxonomy of the genus <i>Polystachya</i> Hook. (Vandeae, Orchidaceae). [PDF]
Sanek K +7 more
europepmc +1 more source
LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li +12 more
wiley +1 more source
Impact of Iron (II) Chloride Treatment on the Physical and Metabolic Changes in Mungbean Sprouts. [PDF]
Park A, Kim BC, Lim SD, Park SH, Ha J.
europepmc +1 more source
Development and characterization of biparental mapping population for the properties of seed and seed coat applicable to seed longevity in soybean (Glycine max (L.) Merrill). [PDF]
Ravikumar RL +5 more
europepmc +1 more source
Two bHLH Transcription Factor Genes AhWSC1a and AhWSC1b Act as Gatekeepers of Testa Pigmentation, Preventing White Seed Coats in Peanuts. [PDF]
Chen G +13 more
europepmc +1 more source
Seed Germination as an Adaptive Response in Halophytes. [PDF]
Şekerci K +3 more
europepmc +1 more source

