Results 41 to 50 of about 32,516 (256)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Horticulture, 2018 The objective of this study was to evaluate seed characteristics of sponge gourd, to establish a core collection of sponge gourd with the germplasm collected throughout the Hatay region.
Kazım MAVİ +3 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
PLoS ONE, 2019 This study describes the use of X-ray fluorescence spectroscopy in Crotalaria ochroleuca seed technology. This work evaluated X-ray fluorescence techniques to estimate the physiological performance of different C.
Mayara Fávero Cotrim +11 more
doaj +1 more source
NS-Kaća: High-protein, very early soybean cultivar [PDF]
Selekcija i Semenarstvo, 2016 NS-Kaća, a new, very early soybean cultivar, has been created at the Institute of Field and Vegetable Crops Novi Sad by crossing domestic and foreign genotypes. The main traits of the cultivar are its early maturity, which placed it into the 000 maturity
Vidić Miloš +3 more
doaj +1 more source
Genotypic variation of dormancy in wheat (Triticum aestivum L.) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science, Department of Plant Science, Massey University, Palmerston North, New Zealand [PDF]
, 1996 Embryo dormancy and α - amylase dormancy are desirable in wheat to minimise pre-harvest sprouting damage. The current work focuses on the embryo and graincoat colour.
Zvomuya, Norman
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
BMC Genomics, 2023 Background Genome-wide association studies (GWAS) are important for the acceleration of crop improvement through knowledge of marker-trait association (MTA).
Charles U. Uba +3 more
doaj +1 more source
Phenotypic Diversity among Croatian Common Bean (Phaseolus vulgaris L.) Landraces [PDF]
, 2015 Phenotypic diversity among Croatian common bean (Phaseolus vulgaris L.) landraces was assessed by analysing 12 qualitative and six quantitative traits in 338 accessions collected from all production areas in Croatia.
Boris Lazarević +5 more
core +1 more source