Results 111 to 120 of about 5,970,847 (335)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

QTL mapping for seed density per silique in Brassica napus. [PDF]

Sci Rep, 2023
Zhu J, Lei L, Wang W, Jiang J, Zhou X.
europepmc   +1 more source

Successful pollinator seed mixes include low grass density and high forb richness across a range of total seeding densities

Restoration Ecology
Pollinator habitat restorations and enhancements are an important approach to mitigate pollinator declines due to habitat loss and other stressors. Foraging resources can be provided by wildflower plantings grown from seed mixes composed of pollinator‐friendly plant species.
Uta Müller, Bethanne Bruninga‐Socolar, Julia Brokaw, Julia Schreiber, Daniel P. Cariveau, Neal M. Williams   +5 more
openaire   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

A study of herbage and seed production of lucerne (Medicago sativa L.) under different plant spacing and cutting treatments : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science at Massey University [PDF]

, 1978
The present study on lucerne cv. "Wairau" was carried out in two separate trials, - a herbage and seed production trial and a seed development trial. The purpose of the first part was to investigate the effect of cutting and spacing on herbage production
Kowithayakorn, Lumyai
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

QTL analysis and candidate gene prediction for seed density per silique by QTL-seq and RNA-seq in spring Brassica napus L. [PDF]

PLoS One, 2023
Xing X, Liu H, Ye J, Yao Y, Li K, Li Y, Du D.   +6 more
europepmc   +1 more source

Winged Seed Aerodynamics and Atmospheric Density: Preliminary Results

International Scholastic Journal of Science, 2023
The relationship between atmospheric density and the aerodynamic behavior of two types of winged seeds, Hopea odorata and Dipterocarpus alatus, have been examined. The seeds were released in atmospheres of air, CO2 , and He and video recorded at 250 fps for analysis.
Siriyada Bundhuratana, Mattaya Hunsreesagul, Atsada Israpanich, Nitchawee Piromchotesiri, Kwanjira Thamakaison   +4 more
openaire   +1 more source

Improvement of Germinated Seed Quality by Density Separation

Journal of the American Society for Horticultural Science, 1985
Abstract Germinated seeds of ‘King Cole’ cabbage ( Brassica oleracea L. ‘Capitata’ ) were separated on a float-sink basis from nongerminated seeds by density differences.
A.G Taylor, T.J. Kenny
openaire   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source