Results 241 to 250 of about 2,278,843 (305)

Yoda1‐Functionalized Nanozymes Coordinate Piezo1 Activation and Mitochondrial Protection to Reprogram the Diabetic Osteoimmune Micromilieu and Promote Vascularized Bone Repair

Advanced Science, EarlyView.
Diabetic bone defects remain a critical clinical challenge. A 3D‐printed BCPG‐MF@Y scaffold, embedding Yoda1‐functionalized manganese dioxide‐ferritin nanozymes, scavenges mtROS, suppresses the cGAS–STING pathway, and reverses cellular senescence, while Yoda1 activates Piezo1 to direct BMSCs fate to synergistically reprogram the osteoimmune ...
Qing‐Song Deng, Ang Wang, Ren Zhang, Xu‐Ran Li, Po‐Lin Liu, Shu‐Hang He, Zi‐Yin Han, Zhi‐Han Shen, Zhan‐Ying Wei, Chang‐Ru Zhang, Fei Wang, Helen Dawes, Jian Lu, Tong‐He Zhu, Jin‐Zhong Zhao, Shang‐Chun Guo, Shi‐Cong Tao   +16 more
wiley   +1 more source

A prospective randomized controlled pilot study of gut microbiome modulation by Nigella sativa seed oil and thymoquinone metabolism in healthy volunteers: implications for gastrointestinal surgery. [PDF]

Sci Rep
El-Banna AF, Junca H, Steube A, Wissenbach DK, Settmacher U, Schneider C, Tekbaş A.   +6 more
europepmc   +1 more source

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

Advanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin, Jiani Li, Panqin Ma, Shinan Wu, Wenying Guan, Yimin Huang, Ke Feng, Mingyan Wei, Zixuan Yang, Shujia Guo, Caihong Huang, Yun‐Long Wu, Yi Han, Zuguo Liu   +13 more
wiley   +1 more source

Quality changes of Huajiao seed oil during refining: A combined approach using traditional methods and multi-omics analysis. [PDF]

Food Chem X
Peng X, Fu B, Liu H, Chen Z, Fang C, Kan J.   +5 more
europepmc   +1 more source

Epithelial SLC25A20 Deficiency Drives Immunosuppressive Neutrophil Remodeling via ARG1 Palmitoylation to Promote Colorectal Cancer

Advanced Science, EarlyView.
SLC25A20 deficiency in tumor cells compromises mitochondrial LCFA transport, which suppresses FAO and drives compensatory release of palmitic acid‐enriched lipids into the TME. These tumor‐derived palmitic acids are taken up by TANs, promoting ZDHHC18‐catalyzed ARG1 palmitoylation.
Yue Han, Tian‐Yuan Tan, Bin Zhang, Ye‐Bin Fu, Wen Chen, Min‐Hui Yang, Yi‐Qing Wang, Yan‐Qing Ding, Shuang Wang   +8 more
wiley   +1 more source

Physicochemical characterization, antioxidant capacity, and antimicrobial activity of Citrullus colocynthis seed oil. [PDF]

Sci Rep
Hoffola AA, Robi AG, Tefera ZT, Abera WG.   +3 more
europepmc   +1 more source

Comprehensive Experimental Investigation of Rosehip (<i>Rosa canina</i> L.) Seed Oil as a Novel Biodiesel Feedstock: Engine Performance, Combustion, Emission, and Exergy Analyses. [PDF]

Glob Chall
Güner E.
europepmc   +1 more source

BnaC03.SEIPIN1 improves seed oil content by increasing the number of lipid droplets in Brassica napus. [PDF]

BMC Plant Biol
Li Y, Cao Z, Xiang Y, Guo L, Zu F, Wang T, Li M, Li B, Lu S.   +8 more
europepmc   +1 more source

<i>Camellia japonica</i> Seed Oil Fermented by <i>Sporidiobolus pararoseus</i> Prevents Skin Cellular Photoaging by Inducing Autophagy. [PDF]

Life (Basel)
Lv B, Meng J, Zhang X, Li G, Gao H, Jiang Y, Zhou Z, Chen G.   +7 more
europepmc   +1 more source

Comparative genomics across <i>Linum</i> illuminates the evolutionary basis of flax domestication, genome diversification, and seed oil biosynthesis. [PDF]

Front Genet
Yi L, Sa R, Mu Y, Zhang J, He R, Song Y, Zhou Y, Chen Y.   +7 more
europepmc   +1 more source