Results 41 to 50 of about 191,044 (310)

The seeding of tau pathology alters the endolysosomal system [PDF]

Alzheimer's & Dementia, 2020
AbstractBackgroundTau pathology and endolysosomal alterations co‐occur in brains of Alzheimer’s Disease and other tauopathy patients, but the relationship between these two pathological features is currently not understood.MethodTau pathology can be modeled in vitro by seeding recombinant tau fibrils on human tau expressing cells, recapitulating tau ...
Sonia Vazquez‐Sanchez, Vera I. Wiersma, Jeroen Kole, Rozemarijn Jongeneel, Roderick van Beek, Maarten Bebelman, Wiep Scheper, Jan van Weering   +7 more
openaire   +1 more source

Loss of intranetwork and internetwork resting state functional connections with Alzheimer\u27s disease progression [PDF]

, 2012
Alzheimer\u27s disease (AD) is the most common cause of dementia. Much is known concerning AD pathophysiology but our understanding of the disease at the systems level remains incomplete.
Ances, Beau M, Benzinger, Tammie L, Brier, Mathew R, Holtzman, David M, Morris, John C, Raichle, Marcus E, Snyder, Abraham Z, Thomas, Jewell B, Zhang, Dongyang   +8 more
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Transmissibilidade e efeito de Acremonium strictum em sementes de milho Transmissibility and effect of Acremonium strictum in maize seeds

Ciência e Agrotecnologia, 2003
Acremonium strictum é patogênico ao milho e a outras culturas, podendo causar podridão de sementes, podridão de colmos e a morte de plântulas. Trata-se de um fungo que pode interferir no vigor, estande e produtividade final das plantas.
Hudson Teixeira, José da Cruz Machado
doaj   +1 more source

Melinjo seed extract increases adiponectin multimerization in physiological and pathological conditions [PDF]

Scientific Reports, 2020
AbstractMelinjo seed extract (MSE) contains large amounts of polyphenols, including dimers of trans-resveratrol (e.g. gnetin C, L, gnemonoside A, B and D), and has been shown to potentially improve obesity. However, there is no clinical evidence regarding the anti-obesity effects of MSE, and its mechanisms are also unclear.
Kentaro Oniki, Taisei Kawakami, Azusa Nakashima, Keishi Miyata, Takehisa Watanabe, Haruka Fujikawa, Ryunosuke Nakashima, Aoi Nasu, Yuka Eto, Noriki Takahashi, Hirofumi Nohara, Mary Ann Suico, Shunsuke Kotani, Yui Obata, Yuki Sakamoto, Yuri Seguchi, Junji Saruwatari, Tadashi Imafuku, Hiroshi Watanabe, Toru Maruyama, Hirofumi Kai, Tsuyoshi Shuto   +21 more
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Detection of Drechslera avenae (Eidam) Sharif [Helminthosporium avenae (Eidam)] in Black Oat Seeds (Avena strigosa Schreb) Using Multispectral Imaging

Sensors, 2020
Conventional methods for detecting seed-borne fungi are laborious and time-consuming, requiring specialized analysts for characterization of pathogenic fungi on seed.
Fabiano França-Silva, Carlos Henrique Queiroz Rego, Francisco Guilhien Gomes-Junior, Maria Heloisa Duarte de Moraes, André Dantas de Medeiros, Clíssia Barboza da Silva   +5 more
doaj   +1 more source

Opportunities in Tajikistan to breed wheat varieties resistant to seed-borne diseases and improved baking quality [PDF]

, 2013
Wheat seed-borne diseases and options for improving baking quality of wheat, as well as the role of genotypes for breeding to achieve high yield and quality are the key issues discussed in this introductory paper.
Husenov, Bahromiddin
core  

Occurrence and diversity of Xanthomonas campestris pv. campestris in vegetable brassica fields in Nepal [PDF]

, 2010
Black rot caused by Xanthomonas campestris pv. campestris was found in 28 sampled cabbage fields in five major cabbage-growing districts in Nepal in 2001 and in four cauliflower fields in two districts and a leaf mustard seed bed in 2003.
Brita Dahl Jensen, Cook A. A., De Bruijn F. J., Hira K. Manandhar, Ignatov A., Joana G. Vicente, Shrestha K., Steven J. Roberts, Versalovic J., Walker J. C., Zaccardelli M.   +10 more
core   +1 more source

Seed pathology of non-domesticated species of tropical ecosystems

Journal of Seed Science, 2022
Abstract: Seed pathology is an area of study that began in the last century and has been developing since then, with increasing contribution especially to agricultural production systems. However, in the environmental area, studies began much later, but showed equal importance, especially for plant restoration and germplasm conservation programs.
Rayana de Sá Martins, Nelson Augustos dos Santos Junior, Claudio José Barbedo   +2 more
openaire   +3 more sources