Results 31 to 40 of about 684 (207)

Inactivation of isolated fungi on Erythrina velutina Willd. seeds through atmospheric plasma

Brazilian Journal of Biology, 2021
This study aimed to evaluate the effect of atmospheric plasma application on the inactivation of fungi on the surface of Erythrina velutina seeds and on isolated fungal colonies. Two experiments were conducted using a completely randomized design. First,
F. E. P. Diógenes, S. R. C. Nascimento, C. Alves Junior, E. P. Paiva, S. B. Torres, A. K. Oliveira, M. M. Q. Ambrósio   +6 more
doaj   +1 more source

Bacterial alarmone (p)ppGpp mediates the pathogenicity of Clavibacter michiganensis via a dual mechanism that affects both enzyme production and the Tat secretion system

mSystems
The gram-positive bacterium Clavibacter michiganensis (Cm) causes bacterial canker of tomato. The infection process of Cm is of considerable interest, and the role of the alarmone guanosine tetraphosphate or pentaphosphate [(p)ppGpp], a global regulator,
Xiaoli Xu, Kaihong Bai, Jia Shi, Chengxuan Yu, Shuang Song, Na Jiang, Jianqiang Li, Laixin Luo   +7 more
doaj   +1 more source

Metformin Attenuates Tau Pathology in Tau-Seeded PS19 Mice

Neurotherapeutics, 2023
Accumulation of neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau is a histopathological hallmark of Alzheimer's disease (AD) and related tauopathies. Growing evidence demonstrated that tau pathology in AD spreads in a prion-like manner. Previous studies showed that metformin might have a positive effect on cognition.
Shuai Zhao, Ziqi Fan, Xinyi Zhang, Zheyu Li, Ting Shen, Kaicheng Li, Yaping Yan, Yunfeng Yuan, Jiali Pu, Jun Tian, Zhirong Liu, Yanxing Chen, Baorong Zhang   +12 more
openaire   +2 more sources

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Detection of Drechslera avenae (Eidam) Sharif [Helminthosporium avenae (Eidam)] in Black Oat Seeds (Avena strigosa Schreb) Using Multispectral Imaging

Sensors, 2020
Conventional methods for detecting seed-borne fungi are laborious and time-consuming, requiring specialized analysts for characterization of pathogenic fungi on seed.
Fabiano França-Silva, Carlos Henrique Queiroz Rego, Francisco Guilhien Gomes-Junior, Maria Heloisa Duarte de Moraes, André Dantas de Medeiros, Clíssia Barboza da Silva   +5 more
doaj   +1 more source

Transcriptomic signature of Alzheimer’s disease tau seed-induced pathology

General physiology and biophysics, 2021
Spreading of tau pathology to anatomical distinct regions in Alzheimer's disease (AD) is associated with progression of the disease. Studies in recent decade have strived to understand the processes involved in this characteristic spread. We recently showed that AD-derived insoluble tau seeds are able to initiate neurofibrillary pathology in transgenic
Nikoleta, Csicsatkova, Peter, Szalay, Katarina, Matyasova, Veronika, Mate, Martin, Cente, Tomas, Smolek, Veronika, Brezovakova, Lucie, Kawecka, Norbert, Zilka, Santosh, Jadhav   +9 more
openaire   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Transmissibilidade e efeito de Acremonium strictum em sementes de milho Transmissibility and effect of Acremonium strictum in maize seeds

Ciência e Agrotecnologia, 2003
Acremonium strictum é patogênico ao milho e a outras culturas, podendo causar podridão de sementes, podridão de colmos e a morte de plântulas. Trata-se de um fungo que pode interferir no vigor, estande e produtividade final das plantas.
Hudson Teixeira, José da Cruz Machado
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source