Modelling seeding and neuroanatomic spread of pathology in amyotrophic lateral sclerosis [PDF]
AbstractThe neurodegenerative disorder amyotrophic lateral sclerosis (ALS) is characterized by the progressive loss of upper and lower motor neurons, with pathological involvement of cerebral motor and, additionally, extra-motor areas, in a clinicopathological spectrum with frontotemporal dementia (FTD).
Sneha Pandya +6 more
openaire +5 more sources
Persistent, symptomless, systemic, and seed-borne infection of lettuce by Botrytis cinerea [PDF]
Experiments are presented which show that Botrytis cinerea, the cause of gray mould disease, is often present in symptomless lettuce plants as a systemic, endophytic, infection which may arise from seed.
Dewey, F. M. +2 more
core +1 more source
The role of regulatory mechanisms for control of plant diseases and food security — case studies from potato production in Britain [PDF]
Being aware of the potentially devastating impacts of plant diseases on food security, governments have designed and employ plant health legislation to prevent or inhibit the worst impacts.
Dehnen-Schmutz, Katharina +3 more
core +1 more source
Metformin Attenuates Tau Pathology in Tau-Seeded PS19 Mice
Accumulation of neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau is a histopathological hallmark of Alzheimer's disease (AD) and related tauopathies. Growing evidence demonstrated that tau pathology in AD spreads in a prion-like manner. Previous studies showed that metformin might have a positive effect on cognition.
Shuai Zhao +12 more
openaire +2 more sources
Acidovorax citrulli is a gram-negative bacterium that infects a wide range of cucurbits causing bacterial fruit blotch (BFB) disease. Copper-based compounds are the most widely-used chemicals for managing BFB and other bacterial diseases in the field ...
Yumin Kan +8 more
doaj +1 more source
Pathogenicity of the root-knot nematode Meloidogyne javanica on potato [PDF]
Host–parasite relationships and pathogenicity of Meloidogyne javanica on potatoes (newly recorded from Malta) were studied under glasshouse and natural conditions. Potato cvs Cara and Spunta showed a typical susceptible reaction to M. javanica under
Castillo, Pablo +3 more
core +2 more sources
Transcriptomic signature of Alzheimer’s disease tau seed-induced pathology
Spreading of tau pathology to anatomical distinct regions in Alzheimer's disease (AD) is associated with progression of the disease. Studies in recent decade have strived to understand the processes involved in this characteristic spread. We recently showed that AD-derived insoluble tau seeds are able to initiate neurofibrillary pathology in transgenic
Nikoleta, Csicsatkova +9 more
openaire +3 more sources
Microdochium albescens may affect the physiological quality of irrigated rice cultivar seeds [PDF]
: Knowledge of the effect of the seedborne inoculum is important for knowing the level of tolerance of the pathogen by the seed. This research evaluated the effect of the incidence of the fungus Microdochium albescens on the physiological quality of the ...
Bruno Tabarelli Scheidt +3 more
doaj +1 more source
MhcII Regulates Transmission of α-Synuclein-Seeded Pathology in Mice
MHCII molecules, expressed by professional antigen-presenting cells (APCs) such as T cells and B cells, are hypothesized to play a key role in the response of cellular immunity to α-synuclein (α-syn). However, the role of cellular immunity in the neuroanatomic transmission of α-syn pre-formed fibrillar (PFF) seeds is undetermined. To illuminate whether
Gonzalez De La Cruz, Elsa +7 more
openaire +2 more sources
Detection Methods of Fungi in Ilex paraguariensis Seeds
There has been an increase in the occurrence of fungal diseases in Ilex paraguariensis A. St.-Hill. (yerba mate) resulting from their domestication. Seed health tests may indicate pathogens prior to sowing, enabling their control.
Gabriela Fernanda Souza +4 more
doaj +1 more source

