Results 61 to 70 of about 191,731 (311)
Arquivos do Instituto Biológico, 2016 RESUMO: O desenvolvimento de pesticidas é uma constante no setor agropecuário, visando oferecer produtos menos agressivos ao meio ambiente e novos princípios ativos, evitando o aparecimento de resistência.
Maria Paula Domene +4 more
doaj +1 more source
Evolutionary plant breeding for low input systems [PDF]
, 2005 Heritable variation is at the heart of the process of evolution. However, variation is restricted in breeding for uniform crop populations using the pedigree line approach. Pedigree lines are successful in agriculture because synthetic inputs are used to
Phillips, Scott, Wolfe, Martin
core +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Microbiology Spectrum, 2021 The alarmone ppGpp plays an important role in the survival of bacteria by triggering the stringent response when exposed to environmental stress. Although Xanthomonas campestris pv.
Kaihong Bai +6 more
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Conventional PCR for detection of Corynespora cassiicola in soybean seeds
Journal of Seed Science, 2016 The fungus Corynespora cassiicola, causal agent of target spot in soybeans, can be transmitted by soybean seeds and as of that point cause severe damage.
Marcella Viana de Sousa +2 more
doaj +1 more source
The Seeds of Doubt: Finding Seeds in Intriguing Places
Frontiers in Medicine, 2021 Introduction: Seeds may be found in gastrointestinal tissue samples, and their multifaceted appearance may be challenging. The aim is to report a rough incidence of pathology samples which show seeds, specify the most frequent sample types and show an ...
Federica Grillo +10 more
doaj +1 more source
Review on the possible interactions of pests, diseases & weeds in cereals grown in organic and conventional agriculture [PDF]
, 2001 Background The demand for organically produced food is outstripping the ability of UK farmers to supply it and the majority is imported. Furthermore, there is a major shortfall in home-produced organic cereals and cereal products, including straw.
Anon
core
Amyloid-β pathology enhances pathological fibrillary tau seeding induced by Alzheimer PHF in vivo
Acta Neuropathologica, 2019 Neuropathological analysis in Alzheimer's disease (AD) and experimental evidence in transgenic models overexpressing frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17) mutant tau suggest that amyloid-β pathology enhances the development of tau pathology.
Cristina Vergara +10 more
openaire +3 more sources