Results 81 to 90 of about 1,092,233 (309)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Synergistic effects of enzymatic debranching and high hydrostatic pressure on the structural and digestive properties of –conjugated linoleic acid microcapsules

Food Chemistry: X
This study explored the effects of enzymatic debranching (ED, 0–12 h) and high hydrostatic pressure (HHP, 300–600 MPa) on the multi-scale structure and in vitro digestibility of lotus seed starch (LS)–conjugated linoleic acid (CLA) microcapsules.
Bailong Wang, Ru Jia, Wenjing Chen, Zebin Guo   +3 more
doaj   +1 more source

Effectiveness of botanical preparations for the control of rice weevil (Sitophilus oryzae) during rice seed storage and their impact on the rice seed viability : a thesis presented in partial fulfilment of the requirements for the degree of Master of Applied Science in Seed Technology at Massey University, Palmerston North, New Zealand [PDF]

, 2001
Food security and the maintenance of seed quality from harvest to planting are key issues for peasant farmers. In Sierra Leone, up to 28% of rice seed can be damaged by rice weevil in the six months storage period.
Sartie, Alieu Mortuwah
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Biological activity of glucosinolate derived compounds isolated from seed meal of Brassica crops and evaluated as plant and food protection agents [PDF]

, 2007
Glucosinolates are amino acid derived allelochemicals characteristic of plants of the order Capparales. These compounds are present in seeds of agriculturally common Brassica crops in varying quantities depending on the species (ref).
Bellostas, N., Casanova, E., Garcia-Mina, J.M., Hansen, L.M., Jørgensen, L.N., Kudsk, P., Madsen, P.H., Sørensen, H., Sørensen, J.C.   +8 more
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Effect of Pansy (Viola x wittrockiana gams) Seeds Colour and Size on their Germination

Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2008
Four commercial seed lots from the Polish seed companies of pansy (Viola x wittrockiana Gams) with low germination capacity were sorted into 2 size fractions: small and large: below 4 mm long and above 4 mm and 3 colour fractions: yellow, brown and dark,
Rosinska AGNIESZKA, Roman HOLUBOWICZ
doaj   +1 more source

Delivering Seeds of 'Orphan' Crops: The Case Studies of Potato and Groundnut in India [PDF]

This paper examines the performance of the Indian seed system in the context of high volume, low value seed, using the case studies of potato and groundnut.
Mathur, Prasoon, Pal, Suresh, Singh, Harbir   +2 more
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Seed Potato Quality Assurance in Ethiopia: System Analysis and Considerations on Quality Declared Assurance Practices

Agriculture
Smallholder potato farmers in Ethiopia do not realize the theoretical yield potential of the crop because they do not benefit from the advantages of using quality seed potato of improved varieties.
Lemma Tessema, Rogers Kakuhenzire, Margaret A. McEwan   +2 more
doaj   +1 more source