A defective ABC transporter of the MRP family, responsible for the bean lpa1 mutation, affects the regulation of the phytic acid pathway, reduces seed myo-inositol and alters ABA sensitivity [PDF]
We previously identified the lpa1 (low phytic acid) 280-10 line that carries a mutation conferring a 90% reduction in phytic acid (InsP6) content. In contrast to other lpa mutants, lpa1(280-10) does not display negative pleiotropic effects.
Bollini, Roberto +10 more
core +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Effect of cryo-storage on germinability and biochemical changes in papaya (Carica papaya L.) seeds
The seeds of papaya, based on seed storage behaviour, are classified under “intermediate seed” category as they exhibit freezing injury even at low moisture content.
P. Sharmela +3 more
doaj +1 more source
Production of Bread Wheat Control of Quality and Safety in Organic Production Chains [PDF]
This leaflet provides a practical overview for producers and others involved in wheat production and storage, on what can be done at these steps to improve the quality and safety of organically pro-duced wheat, in addition to certification and general ...
Brandt, Kirsten +3 more
core
Multi-scale structure, pasting and digestibility of adlay (Coixlachryma-jobi L.) seed starch [PDF]
peer-reviewedThe hierarchical structure, pasting and digestibility of adlay seed starch (ASS) were investigated compared with maize starch (MS) and potato starch (PS).
Chen, Jicheng +5 more
core +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Proteome Analysis of Poplar Seed Vigor. [PDF]
Seed vigor is a complex property that determines the seed's potential for rapid uniform emergence and subsequent growth. However, the mechanism for change in seed vigor is poorly understood.
Hong Zhang +4 more
doaj +1 more source
A study of seed vigour and seedling emergence of maize under field and laboratory conditions : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science at Massey University [PDF]
Maximum yield is obtained from an optimum stand of any crop species. However there are many factors influencing the stand which can broadly be grouped as soil and plant factors. Soil moisture, temperature and aeration influence germination. These factors
Vitheson, Boonnak
core
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Oxidative stability of refrigerated fish pates containing loquat seed extract
This study investigated the effects of hydroethanolic E. japonica seed extracts (EJSE) as inhibitors of lipid and protein oxidation on fish pates subjected to refrigerated storage. Five fish pate formulations were developed.
Jaqueline Piccolo +6 more
doaj +1 more source

