Results 81 to 90 of about 835,492 (301)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Evaluation Plant Yield and Yield Components of Chickpea and Quinoa under Nitrogen and Intercropping Ratios of Chickpea and Quinoa [PDF]

open access: yesپژوهش‌های حبوبات ایران
IntroductionThe practice of growing two or more crops simultaneously in the same field is called intercropping and it is a common feature in traditional farming of small landholders.
Elham Raftari   +3 more
doaj   +1 more source

Is Drought Stress Tolerance Affected by Biotypes and Seed Size in the Emerging Oilseed Crop Camelina?

open access: yesAgronomy, 2020
One of the main advantages of camelina (Camelina sativa (L.) Crantz) is its wide environmental adaptability and extreme drought tolerance. The availability of both winter and spring camelina biotypes, characterized by different seed sizes, raises the ...
Petar Čanak   +8 more
doaj   +1 more source

Effects of Nanosilica Powder from Rice Hull Ash on Seed Germination of Tomato (Lycopersicon esculentum) [PDF]

open access: yes, 2015
open5noNanosilica powders were synthesized from rice hull ash (RHA) and their effects on seed germination of tomato plants were investigated. Synthesized nanosilica powder was subjected to various characterization studies for identification of the size ...
De Silva, Diana Marie   +4 more
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Avaliação do potencial de produção de sementes de acessos de trevo branco Evaluation of the seed production potential of white clover accessions

open access: yesRevista Brasileira de Zootecnia, 2010
Este trabalho foi conduzido com o objetivo de avaliar o potencial de produção de sementes de 25 acessos da coleção básica de trevo-branco provenientes do Departamento de Agricultura dos Estados Unidos.
Rodrigo Ramos Lopes   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Adding manure and zeolite to improve soil chemical properties and increase soybean yield

open access: yesSains Tanah: Journal of Soil Science and Agroclimatology, 2020
Increasing domestic soybean production is an important part of the effort to reduce reliance on imports. One potential area for improvement is developing soybean crops in Alfisols.
Slamet Minardi   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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