Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Seed spacing variability reduces common bean yield
Pesquisa Agropecuária Tropical, 2019 An uneven seed spacing in the sowing row increases the plants intraspecific competition for environmental resources, potentially lowering grain yields.
Mateus Bortoluzi Bisognin +4 more
doaj +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Evaluation of Yield and Yield Components of Fennel (Foeniculum vulgare L.) With the Combined Application of Nitrogen, Phosphorus and Potassium Supplier Bacteria with Mycorrhizal Fungi in Low-Input Cropping System [PDF]
Journal of Agricultural Science and Sustainable Production, 2017 The effect of biofertilizers on the seed yield and yield components of fennel(Foeniculum vulgare L.), was studied as factorial experiment based on randomized complete block design with three replications and twelve treatments at the Research Farm of the ...
F zamani +3 more
doaj
Variability And Correlation Of Agronomic Characters Of Mungbean Germplasm And Their Utilization For Variety Improvement Program Lukman Hakim [PDF]
, 2008 Information on the variability and correlation between agronomic characters of mungbean accessions with their yield are important for supporting breeding program of the plant.
Hakim, L. (Lukman)
core
Genetic Diversity of Selected Upland Rice Genotypes (Oryza sativa L.) for Grain Yield and Related Traits [PDF]
, 2018 Seventy-seven upland rice genotypes including popular cultivars in Nigeria and introduced varieties selected from across rice-growing regions of the world were evaluated under optimal upland ecology.
Adegbehingbe, F. +7 more
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Plant, Soil and Environment, 2010 A 2-year field experiment was conducted under light enrichment and shading conditions to examine the responses of seed yield and yield components distribution across main axis in soybean.
B. Liu +5 more
doaj +1 more source
Effects of Macronutrients on Seed Quality and Profitability Analysis of Sunflower Production in Northwest Pakistan [PDF]
Potassium (K) and phosphorus (P) application to sunflower (Helianthus annus L.) reduced cost of production, increased seed oil and protein concentration, yield and net returns on the K and P deficient soils in Northwest Pakistan.
Almas, Lal K. +3 more
core +1 more source
Heterosis in soybeans for seed yield components and associated traits
, 2002 The objective of this research was to quantify heterosis of agronomic traits and evaluate direct and indirect correlations among seed yield and other traits. A diallel involving six parents was grown in two localities.
Fábio Pandini +2 more
semanticscholar +1 more source