Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Patterned Polyvinyl Alcohol Hydrogel Dressings with Stem Cells Seeded for Wound Healing [PDF]
Tianlin Gao +7 more
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Insecticidal and Enzyme Inhibition Activities of Leaf/Bark Extracts, Fractions, Seed Oil and Isolated Compounds from Triadica sebifera (L.) Small against Aphis craccivora Koch [PDF]
Shudh Kirti Dolma +2 more
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We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Pepper seed germination assessed by combined X-radiography and computer-aided imaging analysis [PDF]
Alessandro Dell’Aquila
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Highly effective adsorption of organic dyes from aqueous solutions on longan seed-derived activated carbon [PDF]
Nguyễn Văn Hùng +7 more
openalex +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Modelling Underlying Energy Demand Trends and Stochastic Seasonality: An Econometric Analysis of Transport Oil Demand in the UK and Japan [PDF]
This paper demonstrates the importance of adequately modelling the Underlying Energy Demand Trend (UEDT) and seasonality when estimating transportation oil demand for the UK and Japan. The structural time series model is therefore employed to allow for a
Lester C Hunt, Yasushi Ninomiya
core
Disruption of glycosylphosphatidylinositol‐anchored lipid transfer protein 15 affects seed coat permeability in Arabidopsis [PDF]
Saet B. Lee, Mi‐Chung Suh
openalex +1 more source

