Results 41 to 50 of about 1,762,405 (367)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Seed Morphology of Three Neotropical Orchid Species of the Lycaste Genus
Seeds, 2023 Neotropical orchids are vulnerable to extinction due to overharvesting, habitat destruction and climate change. However, a basic understanding of orchid seed biology to support conservation efforts is still lacking for most species.
Alejandra Alfaro Pinto +4 more
doaj +1 more source
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
FEBS Letters, EarlyView.miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan +10 more
wiley +1 more source
Environmental Regulation of Weed Seed Dormancy and Germination
Seeds, 2023 Many weeds produce dormant seeds that are unable to complete germination under favourable conditions. There are two types of seed dormancy: primary dormancy (innate dormancy), in which seeds are in a dormant state upon release from the parent plant, and ...
Mirwais M. Qaderi
doaj +1 more source
YBCO single grains seeded by 45° - 45° bridge-seeds of different lengths [PDF]
, 2012 Single grain, (RE)BCO bulk superconductors in large or complicated geometries are required for a variety of potential applications, such as motors and generators and magnetic shielding devices. As a result, top, multi-seeded, melt growth (TMSMG) has been investigated over the past two years in an attempt to enlarge the size of (RE)BCO single grains ...
arxiv +1 more source
Learning to Match Features with Seeded Graph Matching Network [PDF]
arXiv, 2021 Matching local features across images is a fundamental problem in computer vision. Targeting towards high accuracy and efficiency, we propose Seeded Graph Matching Network, a graph neural network with sparse structure to reduce redundant connectivity and learn compact representation.
arxiv
Search-based Crash Reproduction using Behavioral Model Seeding [PDF]
Softw Test Verif Reliab. 30 (2020) e1733, 2019 Search-based crash reproduction approaches assist developers during debugging by generating a test case which reproduces a crash given its stack trace. One of the fundamental steps of this approach is creating objects needed to trigger the crash. One way to overcome this limitation is seeding: using information about the application during the search ...
arxiv +1 more source