Results 131 to 140 of about 719,917 (315)

Feature-Guided Deep Radiomics for Glioblastoma Patient Survival Prediction

Frontiers in Neuroscience, 2019
Glioblastoma is recognized as World Health Organization (WHO) grade IV glioma with an aggressive growth pattern. The current clinical practice in diagnosis and prognosis of Glioblastoma using MRI involves multiple steps including manual tumor sizing ...
Zeina A. Shboul, Mahbubul Alam, Lasitha Vidyaratne, Linmin Pei, Mohamed I. Elbakary, Khan M. Iftekharuddin   +5 more
doaj   +1 more source

Automatic segmentation with detection of local segmentation failures in cardiac MRI [PDF]

currently under press - Scientific Reports (2020), 2020
Segmentation of cardiac anatomical structures in cardiac magnetic resonance images (CMRI) is a prerequisite for automatic diagnosis and prognosis of cardiovascular diseases. To increase robustness and performance of segmentation methods this study combines automatic segmentation and assessment of segmentation uncertainty in CMRI to detect image regions
arxiv  

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

La formación y el emprendimiento respuesta a las nuevas realidades económicas y sociales

Labour & Law Issues, 2016
The current society is permanently proposing new challenges in economics, politics, law and social relations. The new ways of working in Internet, production decentralisation, the difficulty of identifying the subjects of these relations and the ...
Maria Carmen Aguilar del Castillo
doaj   +1 more source

TGGLines: A Robust Topological Graph Guided Line Segment Detector for Low Quality Binary Images [PDF]

arXiv, 2020
Line segment detection is an essential task in computer vision and image analysis, as it is the critical foundation for advanced tasks such as shape modeling and road lane line detection for autonomous driving. We present a robust topological graph guided approach for line segment detection in low quality binary images (hence, we call it TGGLines). Due
arxiv  

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Construction of flaxseed polyphenol nanolipid emulsions as edible coatings and their application in shelf life extension of spiced beef

Food Chemistry: X
Flaxseed polyphenols exhibited antibacterial and antioxidant properties; however, their poor solubility and stability limited their application in food products. Incorporation into nano-emulsions improved their dissolution and encapsulation.
Yan Ma, Nan Wang, Xiaoyong Liu, Xiangjie Ma, Shaohua Meng, Jiansheng Zhao, Jingjing Chen, Lianjun Song, Mingwu Qiao, Xianqing Huang   +9 more
doaj  

MR Volumetry of Lung Nodules: A Pilot Study

Frontiers in Medicine, 2019
Introduction: Computed tomography (CT) is currently the reference modality for the detection and follow-up of pulmonary nodules. While 2D measurements are commonly used in clinical practice to assess growth, increasingly 3D volume measurements are being ...
Jean Delacoste, Vincent Dunet, Gael Dournes, Gael Dournes, Gael Dournes, Alban Lovis, Chantal Rohner, Christel Elandoy, Julien Simons, Olivier Long, Davide Piccini, Davide Piccini, Matthias Stuber, Matthias Stuber, John O. Prior, Laurent Nicod, Catherine Beigelman-Aubry   +16 more
doaj   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source