Results 71 to 80 of about 1,383,033 (265)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

ESC-Track: A computer workflow for 4-D segmentation, tracking, lineage tracing and dynamic context analysis of ESCs

open access: yesBioTechniques, 2017
Embryonic stem cells (ESCs) can be established as permanent cell lines, and their potential to differentiate into adult tissues has led to widespread use for studying the mechanisms and dynamics of stem cell differentiation and exploring strategies for ...
Laura Fernández-de-Manúel   +4 more
doaj   +1 more source

A Large-scale Synthetic Pathological Dataset for Deep Learning-enabled Segmentation of Breast Cancer [PDF]

open access: gold, 2023
Kexin Ding   +5 more
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Performance improvement using an automation system for recognition of multiple parametric features based on human footprint

open access: yesKuwait Journal of Science, 2015
Rapid increase in population growth has made the mankind to delve in appropriate identificationof individuals through biometrics. Foot Print Recognition System is a new challenging areainvolved in the Personal recognition that is easy to capture and ...
AMBETH KUMAR VISAM DEVADOSS   +3 more
doaj  

Tourists' perceptions of beach quality improvement during the off-peak season: a segmentation approach

open access: yesTourism & Management Studies, 2021
Recently coastal tourism has increased dashingly, however, it has negatively affected environmental, social and cultural sustainability. Algarve is the most touristic place in Portugal with a large number of beautiful beaches.
Goda Lukoseviciute   +1 more
doaj  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Image segmentation evaluation using an integrated framework [PDF]

open access: yes, 2007
In this paper we present a general framework we have developed for running and evaluating automatic image and video segmentation algorithms. This framework was designed to allow effortless integration of existing and forthcoming image segmentation ...
Adamek, Tomasz   +3 more
core  

A Tumour and Liver Automatic Segmentation (ATLAS) Dataset on Contrast-Enhanced Magnetic Resonance Imaging for Hepatocellular Carcinoma [PDF]

open access: gold, 2023
Félix Quinton   +11 more
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

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