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Functional crosstalk between the cohesin loader and chromatin remodelers
Nature Communications, 2022 Chromatin remodelers direct the cohesin loader to nucleosome depleted regions where cohesin accesses chromosomes. Muñoz et al. now show that the cohesin loader in turn is a biochemical activator of a chromatin remodeler, helping to clear ...
Sofía Muñoz +5 more
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A Brownian ratchet model for DNA loop extrusion by the cohesin complex
eLife, 2021 The cohesin complex topologically encircles DNA to promote sister chromatid cohesion. Alternatively, cohesin extrudes DNA loops, thought to reflect chromatin domain formation. Here, we propose a structure-based model explaining both activities.
Torahiko L Higashi +4 more
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Frontiers in Genetics, 2021 The formation of hybrid sterility is an important stage of speciation. The voles of the genus Microtus, which is the most speciose genus of rodents, provide a good model for studying the cytological mechanisms of hybrid sterility.
Tatiana I. Bikchurina +7 more
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The large cytoplasmic volume of oocyte
The Journal of Reproduction and Development, 2022 The study of the size of cells and organelles has a long history, dating back to the 1600s when cells were defined. In particular, various methods have elucidated the size of the nucleus and the mitotic spindle in several species.
Hirohisa KYOGOKU, Tomoya S KITAJIMA
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Nature Communications, 2020 Oocyte meiosis must achieve spindle bipolarization without predefined spatial cues. Yoshida et al. demonstrate that spindle bipolarization during meiosis I in mouse oocytes requires kinetochores to prevent chromosome segregation errors, a phenomenon that
Shuhei Yoshida +12 more
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Genome Biology, 2020 Background Structural maintenance of chromosomes (SMC) complexes are central organizers of chromatin architecture throughout the cell cycle. The SMC family member condensin is best known for establishing long-range chromatin interactions in mitosis ...
Yasutaka Kakui +7 more
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Journal of Economic Behavior & Organization, 2007 Schelling (1969, 1971a,b, 1978) considered a simple model with individual agents who only care about the types of people living in their own local neighborhood. The spatial structure was represented by a one- or two-dimensional lattice. Schelling showed that an integrated society will generally unravel into a rather segregated one even though no ...
GIORGIO FAGIOLO +2 more
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Cell-Cycle Regulation of Dynamic Chromosome Association of the Condensin Complex
Cell Reports, 2018 Summary: Eukaryotic cells inherit their genomes in the form of chromosomes, which are formed from the compaction of interphase chromatin by the condensin complex. Condensin is a member of the structural maintenance of chromosomes (SMC) family of ATPases,
Rahul Thadani +4 more
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Gender Segregation in Regional Labour Market: Evidence from South Sumatra Province, Indonesia
Sriwijaya International Journal of Dynamic Economics and Business, 2023 This study aims to examine gender segregation and type of work to measure the overall of segregation and the segregation of several population subgroups, namely education, age, wages, working hours, and area of residence.
Azwardi +4 more
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3D numerical investigation of functionally graded concrete
Ho Chi Minh City Open University Journal of Science - Engineering and Technology, 2023 In the design of engineering structures, concrete is assumed to have homogeneously mechanical properties. However, in reality, the concrete material is usually not uniform with respect to the height of structures because segregation mostly occurs during ...
Nguyen Ngoc Hau, Le Thanh Cuong
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