Results 91 to 100 of about 2,135,140 (326)
Multiple-line inference of selection on quantitative traits
, 2015 Trait differences between species may be attributable to natural selection. However, quantifying the strength of evidence for selection acting on a particular trait is a difficult task.
Berg, Johannes +3 more
core +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Reduction of traits for genetic evaluation of linear described traits in the Old Kladruber horse
Czech Journal of Animal Science, 2012 The estimated genetic parameters were used for selection of important conformation traits and reduction in the number of the described characteristics. For reduction in the number of described traits from the original 36 to 24, the traits were selected ...
L. Vostrý, J. Přibyl, P. Šimeček
doaj +1 more source
Mendelian randomization with fine-mapped genetic data: choosing from large numbers of correlated instrumental variables [PDF]
arXiv, 2017 Mendelian randomization uses genetic variants to make causal inferences about the effect of a risk factor on an outcome. With fine-mapped genetic data, there may be hundreds of genetic variants in a single gene region any of which could be used to assess this causal relationship.
arxiv
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
FEBS Letters, EarlyView.miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan +10 more
wiley +1 more source
Genetics and Molecular Biology, 2005 Few theoretical and experimental studies have analyzed the genetic basis of body size dimorphism. Since the evolutionary response to selection depends of the genetic variance in a population it is to be expected that traits under selection would have ...
Raúl Cueva del Castillo
doaj +1 more source
Direct selection on genetic robustness revealed in the yeast transcriptome. [PDF]
PLoS ONE, 2007 Evolutionary theory predicts that organisms should evolve the ability to produce high fitness phenotypes in the face of environmental disturbances (environmental robustness) or genetic mutations (genetic robustness).
Stephen R Proulx +2 more
doaj +1 more source
FEBS Letters, EarlyView.We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring +6 more
wiley +1 more source
Genetic Optimization of Keywords Subset in the Classification Analysis of Texts Authorship [PDF]
arXiv, 2012 The genetic selection of keywords set, the text frequencies of which are considered as attributes in text classification analysis, has been analyzed. The genetic optimization was performed on a set of words, which is the fraction of the frequency dictionary with given frequency limits.
arxiv
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source