Results 71 to 80 of about 1,164,710 (315)
The effect of genomic information on optimal contribution selection in livestock breeding programs
, 2013 Long-term benefits in animal breeding programs require that increases in genetic merit be balanced with the need to maintain diversity (lost due to inbreeding). This can be achieved by using optimal contribution selection.
Hickey, John M +7 more
core +1 more source
Perfect Simulation From Nonneutral Population Genetic Models: Variable Population Size and Population Subdivision. [PDF]
, 2006 We show how the idea of monotone coupling from the past can produce simple algorithms for simulating samples at a nonneutral locus under a range of demographic models.
Fearnhead, Paul, Paul Fearnhead
core +1 more source
Integrating Selection Mapping With Genetic Mapping and Functional Genomics
Frontiers in Genetics, 2018 Genomic scans for signatures of selection allow us to, in principle, detect variants and genes that underlie recent adaptations. By combining selection mapping with genetic mapping of traits known to be relevant to adaptation, we can simultaneously ...
Martin Johnsson, Martin Johnsson
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Optimizing the selection of quantitative traits in plant breeding using simulation
Frontiers in Plant ScienceThis review summarizes findings from simulation studies on quantitative traits in plant breeding and translates these insights into practical schemes. As agricultural productivity faces growing challenges, plant breeding is central to addressing these ...
Rafael Augusto Vieira +2 more
doaj +1 more source
Detecting selection with a genetic cross [PDF]
Proceedings of the National Academy of Sciences, 2020 Significance Natural selection is the force that underlies the spectacular adaptations of all organisms to their environments. However, not all traits are under selection; a key question is which traits have been shaped by selection, as opposed to the random drift of neutral traits.
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
, 2014 J.S.K. was funded by the Academy of Finland, L.W.S. by the Australian Research Council, J.H. by an Australian Postgraduate Award, and J.L.T. by a postdoctoral research fellowship from the University of Western Australia.Recently, doubt has been cast on ...
Simmons, LW +3 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Selection, maternal effects and inbreeding in reindeer husbandry [PDF]
, 2003 In extensive grazing systems where several owners’ flocks are allowed to mix, selection strategies will also interact, due to gene flow between flocks. The aim of the thesis was to analyse breeding schemes in terms of genetic gain and rate of inbreeding (
Rönnegård, Lars
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