Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
Modular feature selection using relative importance factors [PDF]
Feature selection plays an important role in finding relevant or irrelevant features in classification. Genetic algorithms (GAs) have been used as conventional methods for classifiers to adaptively evolve solutions for classification problems.
Li, P, Guan, SU, Zhu, F
core +1 more source
Selection on milk production and conformation traits during the last two decades in Japan [PDF]
Objective The purpose of this study was to compare intended and actual yearly genetic gains for milk production and conformation traits and to investigate the simple selection criterion practiced among milk production and conformation traits during the ...
Kenji Togashi +7 more
doaj +1 more source
Increasing cassava root yield: Additive-dominant genetic models for selection of parents and clones
Genomic selection has been promising in situations where phenotypic assessments are expensive, laborious, and/or inefficient. This work evaluated the efficiency of genomic prediction methods combined with genetic models in clone and parent selection with
Luciano Rogério Braatz de Andrade +9 more
doaj +1 more source
The genetical theory of multilevel selection [PDF]
Abstract The theory of multilevel selection ( MLS ) is beset with conceptual difficulties. Although it is widely agreed that covariance between group trait and group fitness may arise in the natural world and drive a response to ‘group selection’, ambiguity exists over the ...
openaire +4 more sources
Detecting selection with a genetic cross [PDF]
Significance Natural selection is the force that underlies the spectacular adaptations of all organisms to their environments. However, not all traits are under selection; a key question is which traits have been shaped by selection, as opposed to the random drift of neutral traits.
openaire +2 more sources
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
Mass selection in maize composites by means of selection indices [PDF]
General considerationsA selection index may be applied to selection based either upon the performance of single plants or upon the performance of progenies.
Wolff, F., de
core
Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge +6 more
wiley +1 more source
Spatiotemporal patterns of genetic variation for growth and fertility in Scots pine [PDF]
Genetic testing plays an important role in tree breeding. Understanding basic genetic parameters for growth and fertility is a prerequisite for developing a successful breeding strategy to balance between short- and long-term gains.
Kroon, Johan
core

