Results 61 to 70 of about 5,098,978 (305)

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo   +11 more
wiley   +1 more source

A new genetic algorithm for multi-label correlation-based feature selection. [PDF]

open access: yes, 2015
This paper proposes a new Genetic Algorithm for Multi-Label Correlation-Based Feature Selection (GA-ML-CFS). This GA performs a global search in the space of candidate feature subset, in order to select a high-quality feature subset is used by a multi ...
Jungjit, Suwimol, Freitas, Alex A.
core   +1 more source

The effect of genomic information on optimal contribution selection in livestock breeding programs [PDF]

open access: yes, 2013
Long-term benefits in animal breeding programs require that increases in genetic merit be balanced with the need to maintain diversity (lost due to inbreeding). This can be achieved by using optimal contribution selection.
Hickey, John M   +7 more
core   +1 more source

Perfect Simulation From Nonneutral Population Genetic Models: Variable Population Size and Population Subdivision. [PDF]

open access: yes, 2006
We show how the idea of monotone coupling from the past can produce simple algorithms for simulating samples at a nonneutral locus under a range of demographic models.
Fearnhead, Paul
core   +5 more sources

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens   +6 more
wiley   +1 more source

Males influence maternal effects that promote sexual selection : a quantitative genetic experiment with dung beetles Onthophagus taurus [PDF]

open access: yes, 2014
J.S.K. was funded by the Academy of Finland, L.W.S. by the Australian Research Council, J.H. by an Australian Postgraduate Award, and J.L.T. by a postdoctoral research fellowship from the University of Western Australia.Recently, doubt has been cast on ...
Simmons, LW   +3 more
core   +1 more source

Long-Term Impact of Optimum Contribution Selection Strategies on Local Livestock Breeds with Historical Introgression Using the Example of German Angler Cattle

open access: yesG3: Genes, Genomes, Genetics, 2017
The long-term performance of different selection strategies was evaluated via simulation using the example of a local cattle breed, German Angler cattle.
Yu Wang   +4 more
doaj   +1 more source

Preservation of Genetic Variation in a Breeding Population for Long-Term Genetic Gain

open access: yesG3: Genes, Genomes, Genetics, 2020
Genomic selection has been successfully implemented in plant and animal breeding. The transition of parental selection based on phenotypic characteristics to genomic selection (GS) has reduced breeding time and cost while accelerating the rate of genetic
David Vanavermaete   +3 more
doaj   +1 more source

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho   +6 more
wiley   +1 more source

Spatiotemporal patterns of genetic variation for growth and fertility in Scots pine [PDF]

open access: yes, 2011
Genetic testing plays an important role in tree breeding. Understanding basic genetic parameters for growth and fertility is a prerequisite for developing a successful breeding strategy to balance between short- and long-term gains.
Kroon, Johan
core   +1 more source

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