Results 141 to 150 of about 5,971,359 (314)
Feature Selection via Coalitional Game Theory [PDF]
, 2007 We present and study the contribution-selection algorithm (CSA), a novel algorithm for feature selection. The algorithm is based on the multiperturbation shapley analysis (MSA), a framework that relies on game theory to estimate usefulness. The algorithm
Dror, G., Cohen, S. B., Ruppin, E.
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
GSE’s 50th anniversary: where do we go from now?
Genetics Selection Evolution, 2019 Genetic Selection Evolution’s Editorial Board
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Trial Selection Theory: A Unified Model [PDF]
This paper provides a formal model of the trial selection process that incorporates the Priest-Klein hypothesis and alternative theories of selection.
Keith N. Hylton, Haizhen Lin
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Fisheries and Aquatic SciencesThe mechanism for the elimination of xenobiotics undergoes three different phases of reactions in organisms. Among these, glutathione S-transferases (GSTs) are classified as phase II detoxification enzymes, catalyzing the conjugation of electrophilic ...
Jeongeun Kim +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Genome-wide association studies on leaf midrib architecture in maize
Frontiers in Plant ScienceIntroductionLeaf midrib architecture (LMA) in maize plays essential roles in supporting leaf structure and facilitating photosynthetic performance. Despite its importance for plant architecture and yield potential, the genetic basis underlying key midrib
Dongdong Dang +8 more
doaj +1 more source
A Strategic Selection Procedure [PDF]
A decision maker (DM) wishes to select a competent candidate to fill a position. However, since the wage and task of the position is predetermined, the DM cannot use contract as a screening device.
Toru Suzuki
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