Results 151 to 160 of about 5,971,359 (314)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Scab (Venturia inaequalis (Cooke) G. Winter) lesion on some apple (Malus domestica Borkh.) varieties with Vf gene (Rvi 6) in Oryol region [PDF]

open access: yesАграрный вестник Урала
Dolzhikova   +4 more
doaj   +1 more source

METHOD OF FLUORIMETRIC DETERMINATION OF POTASSIUM CYANATE IN CARBAMYLATED DARBEPOIETIN ALPHA DRUG SUBSTANCE

open access: yesРазработка и регистрация лекарственных средств, 2019
Method of determination of potassium cyanate in carbamylated darbepoietin alpha drug substance was developed. The method is based on derivatization of cyanate by methyl ester of anthranilic acid followed by formation bicyclic derivative (1-H,3-H ...
A. D. Askretkov   +2 more
doaj  

The selection of parliamentary candidates in Belgium

open access: yes, 1985
Papier présenté à l'atelier 'The selection of parliamentary candidates' aux Joint Workshops of the European Consortium for Political Research, Barcelona, mars 1985, 32 ...
The selection of parliamentary candidates   +1 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Supplier selection for strategic supplier development [PDF]

open access: yes
This article describes the application of the analytic hierarchy process (AHP) to the supplier selection decision for the strategic development of lean suppliers at a large German industrial company. In a literature survey and from explorative interviews,
T.C. Fendt   +3 more
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

The development of a method for determining the biological activity of erythropoietin preparations in vitro

open access: yesБиопрепараты: Профилактика, диагностика, лечение, 2018
The method for the assessment of biological activity of erythropoietin preparations in vitro on TF-1 sensitive cells culture has been developed. The special characteristics of measurements and calculations of the biological activity of erythropoietin ...
N. A. Gavrilova   +3 more
doaj  

Mass selection in maize composites by means of selection indices [PDF]

open access: yes, 1972
General considerationsA selection index may be applied to selection based either upon the performance of single plants or upon the performance of progenies.
Wolff, F., de
core  

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