Results 161 to 170 of about 13,377,413 (367)

Exploring the molecular characteristics, detoxification functions, and immune responses of two glutathione S-transferases in redlip mullet (Liza haematochelia)

Fisheries and Aquatic Sciences
The mechanism for the elimination of xenobiotics undergoes three different phases of reactions in organisms. Among these, glutathione S-transferases (GSTs) are classified as phase II detoxification enzymes, catalyzing the conjugation of electrophilic ...
Jeongeun Kim, Welivitiye Kankanamge Malithi Omeka, Qiang Wan, Jehee Lee   +3 more
doaj   +1 more source

On the origin of species by means of natural selection: Or the preservation of the favoured races in the struggle for life.

, 2019
C. Darwin
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Scab (Venturia inaequalis (Cooke) G. Winter) lesion on some apple (Malus domestica Borkh.) varieties with Vf gene (Rvi 6) in Oryol region [PDF]

Аграрный вестник Урала
Dolzhikova, Yanchuk, Galasheva, Korneeva, Pavlenko   +4 more
doaj   +1 more source

Endovascular therapy for ischemic stroke with perfusion-imaging selection.

New England Journal of Medicine, 2015
B. Campbell, P. Mitchell, T. Kleinig, H. Dewey, L. Churilov, N. Yassi, B. Yan, R. Dowling, M. Parsons, T. Oxley, Teddy Y. Wu, M. Brooks, M. Simpson, F. Miteff, C. Levi, M. Krause, T. Harrington, K. Faulder, B. Steinfort, M. Priglinger, T. Ang, R. Scroop, P. Barber, B. McGuinness, T. Wijeratne, T. Phan, W. Chong, R. Chandra, C. Bladin, M. Badve, H. Rice, L. de Villiers, Henry Ma, P. Desmond, G. Donnan, Stephen M. Davis   +35 more
semanticscholar   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The development of a method for determining the biological activity of erythropoietin preparations in vitro

Биопрепараты: Профилактика, диагностика, лечение, 2018
The method for the assessment of biological activity of erythropoietin preparations in vitro on TF-1 sensitive cells culture has been developed. The special characteristics of measurements and calculations of the biological activity of erythropoietin ...
N. A. Gavrilova, S. A. Cherepushkin, N. V. Rykalina, Yu. I. Obukhov   +3 more
doaj  

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Geometrical Vertical Trajectory Optimization – Comparative Performance Evaluation of Phase versus Phase and Altitude-Dependent Preferred Gradient Selection

, 2016
Bogdan Dumitru Dancila, Benoit Beulze, Ruxandra Mihaela Botez   +2 more
openalex   +1 more source