Results 101 to 110 of about 529,543 (309)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Consolidation of Banks in Japan: Causes and Consequences [PDF]
We investigate the motives and consequences of the consolidation of banks in Japan during the period of fiscal year 1990-2004 using a comprehensive dataset.
TSURU Kotaro, HOSONO Kaoru, SAKAI Koji
core
, 2014 J.S.K. was funded by the Academy of Finland, L.W.S. by the Australian Research Council, J.H. by an Australian Postgraduate Award, and J.L.T. by a postdoctoral research fellowship from the University of Western Australia.Recently, doubt has been cast on ...
Simmons, LW +3 more
core +1 more source
COST/BENEFIT ANALYSIS – A TOOL TO IMPROVE RECRUITMENT, SELECTION AND EMPLOYMENT IN ORGANIZATIONS [PDF]
Management & Marketing, 2013 Human resource is a major source for organization to obtain competitive advantage and can be very important in obtaining long-term performance. The limits of recruitment process are the cost, the choice made, time and legislation.
Nicoleta Valentina FLOREA
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 2012 In this study the effects of support consequences (SC) and cultural consequences (CC) on the selection of interlocks (by SC) and interlocking behavioral contingencies (IBCs – by CC) was evaluated.
Zagury Tourinho, Emmanuel; Universidade Federal do Pará +1 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The causes and consequences of reproductive interference in the Lygaeidae
, 2015 Electronic version excludes material for which permission has not been granted by the rights holderReproductive interference occurs when individuals direct sexual behaviours towards other species and this causes a reduction in the fitness of one or both ...
Burdfield-Steel, Emily R.
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Partecipazione e Conflitto, 2014 This research would analyze causes, characteristics and consequences of online primary elections organized by Five Star Movement (M5s), in December 2012, to select its MPs candidates.
Maria Elisabetta Lanzone, Stefano Rombi
doaj +1 more source